Research Project
Grant-in-Aid for Young Scientists (B)
Eosinophilic chronic rhinosinusitis (ECRS) with asthma is known as refractory and recurrence-prone disease. In particular, ECRS patients with severe asthma had elevated levels of fractionated exhaled nitric oxide and reduced response to corticosteroids. Corticosteroid sensitivity was reduced in both bronchial epithelial cells located near inflammatory site and peripheral blood mononuclear cells. Impaired proteins (some phosphatases) involved in regulation of glucocorticoid receptor function may be one of mechanisms.
All 2016 2015 2014
All Journal Article (2 results) (of which Int'l Joint Research: 2 results, Peer Reviewed: 2 results, Acknowledgement Compliant: 2 results, Open Access: 1 results) Presentation (7 results) (of which Invited: 3 results)
Respiratory Research
Volume: 17 Issue: 1 Pages: 30-30
10.1186/s12931-016-0349-0
Journal of Asthma
Volume: 52 Issue: 10 Pages: 1060-1064
10.3109/02770903.2015.1054404