Sarcopenia for the new atherosclerosis risk factor

• Project/Area Number: 26860482
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: General internal medicine(including psychosomatic medicine)
• Research Institution: Ehime University
• Principal Investigator: Ochi Masayuki 愛媛大学, 医学部附属病院, 講師(病院教員) (80648171)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000); Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
• Keywords: サルコペニア / 大腿筋断面積 / 動脈硬化 / 予防 / 大腿筋肉量

Outline of Final Research Achievements

We researched pulse wave velocity, carotid ultrasonography, thigh muscle cross-sectional area measurement, evaluation of cognitive function, blood tests, lifestyle check for participants in anti-aging medical checkup programs and got new insights for correlation sarcopenia and atherosclerosis risk.
It is useful for prevention of sarcopenia and atherosclerosis and we should be going to develop further.

Research Products

• [Journal Article] Muscle mass decline, arterial stiffness, white matter hyperintensity, and cognitive impairment: Japan Shimanami Health Promoting Program study. (2017)
  • Author(s): Kohara K, Okada Y, Ochi M, Ohara M, Nagai T, Tabara Y, Igase M.
  • Journal Title: J Cachexia Sarcopenia Muscle. Volume: - Issue: 4 Pages: 557-566
  • DOI: 10.1002/jcsm.12195
  • NAID: 120006822491
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Office-based simple frailty score and central blood pressure predict mild cognitive impairment in an apparently healthy Japanese population: J-SHIPP study. (2017)
  • Author(s): Ohara M, Kohara K, Okada Y, Ochi M, Nagai T, Ohyagi Y, Tabara Y, Igase M.
  • Journal Title: Sci Rep. Volume: 7 Issue: 1 Pages: 46419-46419
  • DOI: 10.1038/srep46419
  • NAID: 120006305755
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Association of office-based frailty score with hypertensive end organ damage in the J-SHIPP cross-sectional study. (2016)
  • Author(s): Tabara Yasuharu, Katsuhiko Kohara, Masayuki Ochi, Yoko Okada, Maya Ohara, Tokihisa Nagai, Michiya Igase
  • Journal Title: International Journal of Cardiology Volume: 216 Pages: 25-31
  • DOI: 10.1016/j.ijcard.2016.04.135
  • Peer Reviewed / Open Access
• [Journal Article] 心血管疾患治療におけるフレイルの重要性 (2015)
  • Author(s): 越智雅之、小原克彦
  • Journal Title: 内科系総合雑誌 Modern Physician Volume: 未