Project/Area Number |
26860508
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Gastroenterology
|
Research Institution | The University of Tokushima |
Principal Investigator |
KITAMURA Shinji 徳島大学, 大学院医歯薬学研究部, 助教 (60564490)
|
Project Period (FY) |
2014-04-01 – 2016-03-31
|
Project Status |
Completed (Fiscal Year 2015)
|
Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | Barrett腺癌 / 分子イメージング |
Outline of Final Research Achievements |
We aim to make an endoscopic diagnosis system of Barrett's carcinomas or precancerous lesions by using a molecular Imaging in this study. Cases of Barrett's carcinomas are limited, so we carried out basic research using the colon cancer cells, which are relatively easy to collect,at first. The EGFR is exposed high frequency in colon cancer, we dicided to use the EGFR for the target of molecular imaging. We have established the method of EGFR molecular imaging of colonic cancer.We apply same method for Barrett's carcinoma. However, EGFR expression is not necessarily high in Barrett's carcinoma, imaging in the EGFR has been difficult. The new molecular target of Barrett's carcinoma is required, we are advances the current continue to study.
|