Elucidation of morphometric changes of cirrhosis related with nonalcoholic steatohepatitis

• Project/Area Number: 26860539
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Gastroenterology
• Research Institution: Kanazawa University
• Principal Investigator: OZAKI KUMI 金沢大学, 医学系, 協力研究員 (00714651)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
• Keywords: 非アルコール性脂肪肝炎 / 肝硬変 / アルコール性肝硬変 / 肝炎ウイルス

Outline of Final Research Achievements

Morphometric changes of cirrhosis display different patterns according to etiology (hepatitis virus infection, alcoholism, and nonalcoholic steatohepatitis). Differences between etiologies would decrease with progression of cirrhosis.

Research Products

• [Journal Article] Extrahepatic Arteries Originating from Hepatic Arteries: Analysis Using CT During Hepatic Arteriography and Visualization on Digital Subtraction Angiography. (2017)
  • Author(s): Ozaki K, Kobayashi S, Matsui O, Minami T, Koda W, Gabata T.
  • Journal Title: Cardiovasc Intervent Radiol. Volume: 印刷中 Issue: 6 Pages: 822-830
  • DOI: 10.1007/s00270-017-1568-6
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Hepatocyte nuclear factor 1α-inactivated hepatocellular adenomas exhibit high 18F-fludeoxyglucose uptake associated with glucose-6-phosphate transporter inactivation (2016)
  • Author(s): Kumi Ozaki, Kenichi Harada, Noboru Terayama, Osamu Matsui, Satoshi Saitoh,Yoshito Yomimaru, Takeshi Fujii, Toshifumi Gabata.
  • Journal Title: Br J Radiol Volume: 89 Issue: 1063 Pages: 20160265-20160265
  • DOI: 10.1259/bjr.20160265
  • Peer Reviewed / Open Access
• [Journal Article] Morphometric changes in liver cirrhosis: aetiological differences correlated with progression (2016)
  • Author(s): Ozaki K, Matsui O, Kobayashi S, Minami T, Kitao A, Gabata T
  • Journal Title: British Journal of Radiology Volume: 89 Issue: 1059 Pages: 20150896-20150896
  • DOI: 10.1259/bjr.20150896
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Magnetic resonance imaging of an endometrial (2016)
  • Author(s): Ozaki K, Gabata T
  • Journal Title: Journal of Obstetrics and Gynaecology Research Volume: 42(1) Issue: 1 Pages: 99-102
  • DOI: 10.1111/jog.12838
  • Peer Reviewed
• [Journal Article] IgG4-related disease: Dataset of 235 consecutive patients. (2015)
  • Author(s): Inoue D, Yoshida K, Yoneda K., et al.
  • Journal Title: Medicine (Baltimore), in press Volume: / Issue: 15 Pages: e680-e680
  • DOI: 10.1097/md.0000000000000680
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 脾臓摘出術を先行した横隔膜浸潤を伴う脾悪性リンパ腫の1例 (2015)
  • Author(s): 寺川 裕史, 小林 隆司, 所 智和, 竹下 雅樹, 堀川 直樹, 大澤 幸治, 尾崎 公美, 小林 佳子, 寺山 昇, 岡田 英吉, 薮下 和久
  • Journal Title: 癌と化学療法 Volume: 42 Pages: 1836-1838
  • Peer Reviewed
• [Presentation] Morphometric analyses of small accessory liver lobes (2017)
  • Author(s): Kumi Ozaki, Jun Yoshikawa, Toru Yamamoto, Yuki Hattori, Tomohiro Kotsuji, Akira Izuimosaki
  • Organizer: 第76回日本医学放射線学会総会
  • Place of Presentation: 横浜
  • Year and Date: 2017-04-13
• [Presentation] 肝硬化性血管腫の1例 (2017)
  • Author(s): 尾崎公美、山本亨、服部由紀、小辻知広、出雲崎晃、前田一也、加藤嘉一郎、海崎泰治、原季枝
  • Organizer: 第66回日本消化器画像診断研究会
  • Place of Presentation: 東京
• [Presentation] Hepatocyte nuclear factor 1α不活化型肝細胞腺腫におけるFDG-PET集積機序に関す る検討 (2016)
  • Author(s): 尾崎公美, 原田憲一, 松井修,寺山昇, 斎藤聡, 藤井丈士, 吉川淳, 山本亨, 服部由紀
  • Organizer: 第48回日本臨床分子形態学会総会・学術集会
  • Place of Presentation: 熊本
  • Year and Date: 2016-09-23
• [Presentation] A case of unclassified hepatocellular adenomatosis with glucose intolerance (2016)
  • Author(s): 尾崎公美, 吉川淳, 原田憲一, 松井修, 山本亨, 服部由紀, 髙田健次, 小坂康夫, 青柳裕之, 海崎泰治
  • Organizer: 第30回腹部放射線研究会
  • Place of Presentation: 金沢
  • Year and Date: 2016-06-24
• [Presentation] Extrahepatic arteries originating from hepatic arteries: analysis using CT during hepatic arteriography and their visualization on digital subtraction angiography (2016)
  • Author(s): Kumi Ozaki, Satoshi Kobayashi, Osamu Matsui,Tetsuya Minami, Jun Yoshikawa, Toru Yamamoto, Yuki Hattori, Kenji Takada,Yasuo Kosaka, Toshifumi Gabata
  • Organizer: 第75回日本医学放射線学会総会
  • Place of Presentation: 横浜
  • Year and Date: 2016-04-14
• [Presentation] Hepatocyte nuclear factor 1α-inactivated hepatocellular adenomas exhibit high 18F-fluorodeoxyglucose uptake associated with glucose-6-phosphate transporter deactivation (2016)
  • Author(s): Kumi Ozaki, Osamu Matsui, MD, Satoshi Kobayashi, Wataru Koda, Tetsuya Minami, Toshifumi Gabata
  • Organizer: European Congress of Radiology
  • Place of Presentation: Austria Center Vienna
  • Year and Date: 2016-03-02
  • Int'l Joint Research
• [Presentation] Hepatocyte nuclear factor 1α不活化型肝細胞腺腫におけるFDG-PET集積機序に関する検討 (2016)
  • Author(s): 尾崎 公美、原田 憲一、松井 修、寺山 昇、斎藤 聡、藤井 丈士、吉川 淳、山本 亨、服部 由紀、髙田 健次、小坂 康夫
  • Organizer: 第22回肝血流動態・機能イメージ研究会
  • Place of Presentation: 東京ビッグサイト
  • Year and Date: 2016-02-06
• [Presentation] 性状の異なる2病変を呈した後腹膜inflammatry myofibroblastic tumorの1例 (2016)
  • Author(s): 尾崎公美、吉川淳、山本亨、服部由紀、髙田健次、小坂康夫、前田一也、加藤喜一郎、海崎泰治
  • Organizer: 日本医学放射線学会 第１５９回中部地方会
  • Place of Presentation: 名古屋市立大学
  • Year and Date: 2016-01-30
• [Presentation] Hepatocyte nuclear factor 1α不活化型肝細胞腺腫におけるFDG-PET集積機序に関する検討 (2015)
  • Author(s): 尾崎公美、寺山昇、原田憲一、斎藤聡、松井修、藤井丈士、吉川淳、山本亨、服部由紀、髙田健次、小坂康夫
  • Organizer: 第51回日本医学放射線学会秋季臨床大会
  • Place of Presentation: 岩手県盛岡市
  • Year and Date: 2015-10-02
• [Presentation] 肝癌の画像診断 (2015)
  • Author(s): 尾﨑 公美
  • Organizer: 平成26年度生活習慣病検診従事者講習会
  • Place of Presentation: 高岡市民病院、高岡
  • Year and Date: 2015-01-21
  • Invited
• [Presentation] FDG-PETで集積を認めた肝腫瘍の一切除例 (2014)
  • Author(s): 尾崎公美、寺山 昇、小林佳子、野手雅幸、薮下和久、堀川直樹、小林隆司、竹下雅樹、寺川裕史、所智和、伊藤博行、芳尾幸松、中谷敦子、大澤幸治、高木宏明、岡田 英吉、常山幸一
  • Organizer: 第131回北陸肝胆膵年度末大会
  • Place of Presentation: ニューグランドホテル、金沢
  • Year and Date: 2014-12-06
• [Presentation] Morphometric changes in liver cirrhosis: etiological differences correlated with progression (2014)
  • Author(s): 尾崎公美、松井修、蒲田敏文、小林聡、香田渉、南哲弥
  • Organizer: 第72回日本医学放射線学会総会
  • Place of Presentation: パシフィコ横浜、横浜
  • Year and Date: 2014-04-10 – 2014-04-14