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Novel System to Detect Bacteria in Real Time in Dialysis fluid production process

Research Project

Project/Area Number 26860642
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Kidney internal medicine
Research InstitutionJunshin Gakuen University

Principal Investigator

NARAMURA TOMOTAKA  純真学園大学, 保健医療学部, 講師 (60632338)

Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords透析液 / 清浄化 / 細菌 / 自家蛍光 / リアルタイム / 人工透析
Outline of Final Research Achievements

Bacteria tests are conducted in quality control of dialysis fluid for hemodialysis treatment. But regular cultivation method take long period of time to obtain results and has a problem of not being able to count bacteria which are difficult to cultivate. I have focused on the auto-fluorescence substance in the bacteria, to use its auto-fluorescence allowing us to develop a system to measure the bacteria in real-time, without any pretreatments nor addition of any reagents.
I have tested using actual dialysis fluid production process, and it has shown good detection capability. I believe that this system will become the next generation bacteria detection system to dialysis fluid production process where real time and on-site detection is needed.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (11 results)

All 2016 2015 2014

All Journal Article (1 results) (of which Open Access: 1 results) Presentation (8 results) (of which Int'l Joint Research: 2 results,  Invited: 5 results) Book (2 results)

  • [Journal Article] 細菌の自家蛍光を利用した細菌リアルタイムモニタリング2015

    • Author(s)
      楢村友隆
    • Journal Title

      日本血液浄化技術学会雑誌

      Volume: 23 Pages: 357-361

    • Related Report
      2015 Annual Research Report
    • Open Access
  • [Presentation] Recent Trends in Dialysis Fluid2015

    • Author(s)
      Tomotaka Naramura
    • Organizer
      Keimyung University Dongsan Kidney Institute Symposium“Therapeutic Options for Hemodialysis / Online Hemodiafiltration”
    • Place of Presentation
      Daegu, Koria
    • Year and Date
      2015-12-06
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] PurificationDialysis Fluid Purification.2015

    • Author(s)
      Tomotaka Naramura
    • Organizer
      The Cambodian and International Seminar for Nephrology and Dialysis 2015
    • Place of Presentation
      Phnom Penh, Cambodia
    • Year and Date
      2015-09-22
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 透析液清浄化の最前線2015

    • Author(s)
      楢村友隆
    • Organizer
      第17回北部九州透析工学研究会
    • Place of Presentation
      福岡県北九州市
    • Year and Date
      2015-08-20
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 透析液はいつもおなじ?-水質の推移と管理方法について再考する-2015

    • Author(s)
      楢村友隆
    • Organizer
      第25回日本臨床工学会
    • Place of Presentation
      福岡県福岡市
    • Year and Date
      2015-05-23
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 細菌の自家蛍光を利用した細菌リアルタイムモニタリング2015

    • Author(s)
      楢村友隆
    • Organizer
      第42回日本血液浄化技術学会
    • Place of Presentation
      東京都千代田区
    • Year and Date
      2015-04-25
    • Related Report
      2015 Annual Research Report
  • [Presentation] オンラインHDF治療における微生物迅速高精度モニタリング技術の展望2015

    • Author(s)
      楢村友隆
    • Organizer
      第31回日本医工学治療学会
    • Place of Presentation
      広島県広島市
    • Year and Date
      2015-03-28
    • Related Report
      2014 Research-status Report
  • [Presentation] 透析液清浄化のためのエンドトキシン・微生物迅速検査の現状とグローバルな展開2014

    • Author(s)
      楢村友隆
    • Organizer
      第20回日本エンドトキシン・自然免疫研究会
    • Place of Presentation
      東京都文京区
    • Year and Date
      2014-12-06
    • Related Report
      2014 Research-status Report
  • [Presentation] 新手法による透析液中に存在する細菌の迅速高精度モニタリング2014

    • Author(s)
      楢村友隆
    • Organizer
      第59回日本透析医学会
    • Place of Presentation
      兵庫県神戸市
    • Year and Date
      2014-06-14
    • Related Report
      2014 Research-status Report
    • Invited
  • [Book] 最新透析医療:先端技術との融合2016

    • Author(s)
      楢村友隆
    • Total Pages
      859
    • Publisher
      医薬ジャーナル社
    • Related Report
      2015 Annual Research Report
  • [Book] 透析液清浄化に向けて2015

    • Author(s)
      楢村友隆
    • Total Pages
      239
    • Publisher
      医薬ジャーナル社
    • Related Report
      2015 Annual Research Report

URL: 

Published: 2014-04-04   Modified: 2017-05-10  

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