| Project/Area Number |
26860902
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Dermatology
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| Research Institution | Okayama University (2015-2016)
Kinki University (2014) |
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Principal Investigator |
Shuta Tomida 岡山大学, 医歯薬学総合研究科, 准教授 (10372111)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 細菌叢 / NGS / 皮膚 / ニキビ / 比較ゲノム / 次世代シーケンサー / メタゲノム解析 / 比較ゲノム解析 / パンゲノム解析 / マイクロバイオーム / 次世代シークエンサー / アクネ菌 / プロバイオティクス / 共生細菌叢 |
|---|
| Outline of Final Research Achievements |
We have developed a series of protocol to analyze skin microbiome with highly reproducible manner using NGS, providing the basic idea of skin microbiome taken from Japanese people. In addition, based on the highly accurate draft genomes of the bacteriophages of Propionibacterium acnes, we succeeded in extraction of unique genome sequences that could affect the sensitivity to the phage infection. These results could shed light on the development of novel treatment against drug resistant P. acnes
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