Expression of activation-induced cytidine deaminase in cutaneous squamous cell carcinoma
Project/Area Number |
26860908
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Dermatology
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Research Institution | University of Occupational and Environmental Health, Japan |
Principal Investigator |
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Project Period (FY) |
2014-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
|
Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 有棘細胞癌 / 転移 / AID |
Outline of Final Research Achievements |
To examine whether AID (activation-induced deaminase) is expressed in human squamous cell carcinoma (SCC), we performed an anti-AID immunostaining. Forty nine SCC tumors out of 97 cases were AID positive. All tumors in 8 cases with local recurrence expressed AID. All SCC specimens in 14 cases with lymph node metastasis and 2 cases with lung metastasis were positive for anti-AID immunostaining. Taken together, AID expression may be a prognostic marker for cutaneous SCC.
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Report
(3 results)
Research Products
(7 results)
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[Journal Article] Nivolumab in the treatment of malignant melnoma: review of the literature2015
Author(s)
Mashima E, Inoue A, Sakuragi Y, Yamaguchi T, Sasaki N, Hara Y, Omoto D, Ohmori S, Haruyama S, Sawada Y, Yoshioka M, Nishio D, Nakamura M
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Journal Title
Onco Targets Ther
Volume: 8
Pages: 2045-2051
DOI
Related Report
Peer Reviewed
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[Presentation] Expression of AID in malignant melanoma with BRAFV600E mutation2015
Author(s)
Nakamura M, Mashima E, Sakuragi Y, Saito N, Yamaguchi T, Watabe R, Yoshioka H, Omoto D, Hiromasa K, Haruyama S, Kubo R, Yoshioka M, Nishio D
Organizer
23rd World Congress of Dermatology
Place of Presentation
バンクーバー (カナダ)
Year and Date
2015-06-12
Related Report
Int'l Joint Research
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