• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Genome-wide association study of plasma total homocysteine in schizophrenia

Research Project

Project/Area Number 26860931
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Psychiatric science
Research InstitutionThe University of Tokushima

Principal Investigator

KINOSHITA Makoto  徳島大学, 大学病院, 特任助教 (40622478)

Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords統合失調症 / ホモシステイン / ゲノムワイド遺伝子関連解析 / 遺伝子多型
Outline of Final Research Achievements

Homocysteine is a sulfur amino acid and a key substance in the methionine cycle.Previous meta-analyses of association studies between blood homocysteine and schizophrenia have demonstrated an elevated blood homocysteine level in schizophrenia.We conducted a genome-wide association study in 384 patients with schizophrenia.We found novel associations of 3 SNPs with the plasma total homocysteine levels.This is the first genome-wide association study of the plasma total homocysteine in patients with schizophrenia.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (3 results)

All 2015

All Presentation (3 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] Genome-wide association study of plasma total homocysisteine and schizophrenia.2015

    • Author(s)
      Makoto Kinoshita
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      Chicago(United States of America)
    • Year and Date
      2015-10-17 – 2015-10-21
    • Related Report
      2014 Research-status Report
  • [Presentation] Genome-wide association study of plasma total homocysisteine in schizophrenia.2015

    • Author(s)
      Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, Akira Nishi, Issei Imoto, and Tetsuro Ohmori
    • Organizer
      Society for Neruroscience
    • Place of Presentation
      Chicago (USA)
    • Year and Date
      2015-10-17
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ホモシステインに着目した統合失調症病態解析研究2015

    • Author(s)
      木下誠
    • Organizer
      日本生物学的精神医学会
    • Place of Presentation
      タワーホール長堀(東京江戸川区)
    • Year and Date
      2015-09-24
    • Related Report
      2015 Annual Research Report 2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2017-05-10  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi