| Project/Area Number |
26860968
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Hirosaki University |
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Principal Investigator |
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| Research Collaborator |
TAKAI Yoshihiro 一般財団法人 脳神経疾患研究所, 南東北BNCT研究センター, センター長
SATOU Mariko 弘前大学, 大学院医学研究科, 助教
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 低酸素 / 肝細胞癌 / 低酸素細胞 |
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| Outline of Final Research Achievements |
Previous studies reported that cancer cell get theraputic resistance in hypoxia. Hepatocellular carcinoma has same report.In this study,we investigated the efficancy ofcombination of YC-1 and drug eluting beads.We could not find good conditions of
conbination of these. On the other hand, we investigated other drug.We find that metformin improve theraputic resistance of hepatocellular carcinom in hypoxia.
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