Investigation of appropriate radiation dose in low-dose abdominal CT with an iterative reconstruction technique

• Project/Area Number: 26860995
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Osaka Medical College
• Principal Investigator: Nakamoto Atsushi 大阪医科大学, 医学部, 助教 (20625199)
• Research Collaborator: YOSHIKAWA SHUSHI ; JURI HIROSHI ; TANAKA YOSHIKAZU
• Project Period (FY): 2014-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
• Keywords: CT / 逐次近似再構成法 / 低線量 / 放射線被曝 / 逐次近似画像再構成 / 低線量CT

Outline of Final Research Achievements

The purpose of this study was to investigate the appropriate radiation dose for the low-dose abdominal CT with an iterative reconstruction (IR) technique.
The diagnostic performance of abdominal CT with IR and filtered back projection (FBP) was evaluated with radiologists, and the results showed that there was no significant difference in the diagnostic ability between IR and FBP for the same dose. Moreover, the diagnostic ability significantly decreased in images reconstructed with IR with a half dose compared to images reconstructed with FBP with a standard-dose. An aggressive dose reduction may impair the diagnostic performance even with an IR technique.

Research Products

• [Journal Article] Diagnostic performance of reduced-dose CT with a hybrid iterative reconstruction algorithm for the detection of hypervascular liver lesions: a phantom study. (2017)
  • Author(s): Nakamoto A, Tanaka Y, Juri H, Nakai G, Yoshikawa S, Narumi Y.
  • Journal Title: Eur Radiol Volume: 印刷中 Issue: 7 Pages: 2995-3003
  • DOI: 10.1007/s00330-016-4687-6
  • Peer Reviewed
• [Journal Article] Clinical evaluation of image quality and radiation dose reduction in upper abdominal computed tomography using model-based iterative reconstruction; comparison with filtered back projection and adaptive statistical iterative reconstruction. (2015)
  • Author(s): Nakamoto A, Kim T, Hori M, Onishi H, Tsuboyama T, Sakane M, Tatsumi M, Tomiyama N
  • Journal Title: Eur J Radiol Volume: 84 Issue: 9 Pages: 1715-1723
  • DOI: 10.1016/j.ejrad.2015.05.027
  • Peer Reviewed
• [Journal Article] Low-Dose Pelvic Computed Tomography Using Adaptive Iterative Dose Reduction 3-Dimensional Algorithm: A Phantom Study (2015)
  • Author(s): Onishi H, Kockelkoren R, Kim T, Hori M, Nakamoto A, Tsuboyama T, Sakane M, Tatsumi M, Uranishi A, Tanaka T, Taniguchi A, Enchi Y, Satoh K, Tomiyama N
  • Journal Title: J Comput Assist Tomogr Volume: 39 Issue: 4 Pages: 629-634
  • DOI: 10.1097/rct.0000000000000242
  • Peer Reviewed