| Project/Area Number |
26860997
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Radiation science
|
|---|
| Research Institution | Kobe University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Keywords | 放射線治療 / 放射線防護 / 膵がん / スペーサー / 還元型CoQ10 / 粒子線治療 / 腸管防護 |
|---|
| Outline of Final Research Achievements |
Radiotherapy for pancreatic cancer is difficult to deliver curative dose because of risk organs surrounded pancreas. To overcome this problem, we developed a novel radiotherapy method using a novel absorbable spacer. And, we also confirmed the radioprotective effect using Reduced CoQ10. From our experiments, a novel spacer can reduce the radiation damage of intestine, and Reduced CoQ10 can suppress the generation of apoptosis induced by radiation in the intestine. As a result, the survival rate of an experimental animal in this study was improved.
|
