| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Outline of Final Research Achievements |
Cardiac toxicity after definitive chemoradiotherapy for esophageal cancer is a critical issue. To develope of the safe of intensity modulation radiation therapy (IMRT) technique for esophageal cancer, we studied the esophageal motion during free-breathing and breath-hold. During free-breathing, esophageal motion in the superior-inferior direction in all sites was large, compared to the other directions, and amplitudes showed substantial inter-individual variability. The breath-hold technique is feasible for minimizing esophageal displacement during radiotherapy. And, we studied the feasibility of IMRT for esophageal cancer.IMRT for thoracic esophageal cancer achieved better dose conformity for PTV and significant high irradiated dose reduction for heart and liver compared with conventional 3D-CRT with suppressing the low irradiated area to the lung within tolerance level.
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