MR lymphangiography using gadolinium (GD) -DTPA - nanodiamond particles
| Project/Area Number |
26861019
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Tokai University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | ナノダイヤモンド / MRI / リンパ管造影 / MRリンパ管造影 / 造影剤 |
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| Outline of Final Research Achievements |
Techniques to visualize the lymphatic system have lagged behind imagings of the cardiovascular system. Our purpose is to use the gadolinium (GD) -diethylenetriaminepentaacetic acid (DTPA) -nanodaiamond (ND) to safely and effectively image the lymphatics on magnetic resonance (MR) lymphangiography. MRI experiments on the GD-DTPA-ND particles indicated their high signal intensity on T1-weighted images. GD-DTPA-ND cell viability test shows the comparable result with existing GD-DTPA. Now, MR lymphangiography using the GD-DTPA-ND in small animal model is currently in progress.
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Report
(3 results)
Research Products
(65 results)
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[Journal Article] Basic Fibroblast Growth Factor as a Potential Stent Coating Material Inducing Endothelial Cell Proliferation2014
Author(s)
Kitamura, N., Hasebe, T., Matsumoto, T, Hotta, A., Suzuki, T., Yamagami, T. & Terada, H.
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Journal Title
Journal of Atherosclerosis and Thrombosis
Volume: 21
Issue: 5
Pages: 477-485
DOI
NAID
ISSN
1340-3478, 1880-3873
Related Report
Peer Reviewed
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[Presentation] 胸部IVRのＴｏｐｉｃｓ2016
Author(s)
長谷部光泉，松本知博，嶺 貴彦
Organizer
第1回呼吸器血管内治療研究会
Place of Presentation
新宿国際ビルディング (東京都新宿区)
Year and Date
2016-02-27
Related Report
Invited
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[Presentation] 医工産学連携による血管内治療デバイスの開発2015
Author(s)
長谷部光泉, 松本知博, 嶺 貴彦，堀田 篤, 鈴木哲也
Organizer
平成27年度新規事業「ものづくり中小企業・小規模事業者連携支援事業」 第6回連携クラスターサロン
Place of Presentation
西武信用金庫八王子支店 (東京都八王子市)
Year and Date
2015-12-02
Related Report
Invited
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[Presentation] 門脈血栓症治療後に再灌流症候群を起こした1例2015
Author(s)
伊藤 裕幸, 水上 創, 永田 順子, 小嶋清一郎, 高清水眞二, 渡辺勲史, 松本 知博, 長谷部 光泉, 幕内博康
Organizer
第22回日本門脈圧亢進症学会総会
Place of Presentation
パシフィコ横浜 (神奈川県横浜市)
Year and Date
2015-09-10
Related Report
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[Presentation] DEB-TACEの基礎知識2015
Author(s)
長谷部光泉，松本知博，嶺 貴彦，渡辺勲史
Organizer
第22回日本門脈圧亢進症学会総会
Place of Presentation
パシフィコ横浜 (神奈川県横浜市)
Year and Date
2015-09-10
Related Report
Invited
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[Presentation] B-TACE2015
Author(s)
松本知博，嶺貴彦，長谷部光泉
Organizer
第3回IVR同志会
Place of Presentation
ホテル ザ・エルシィ町田 (東京都町田市)
Year and Date
2015-08-29
Related Report
Invited
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[Presentation] Balloon-occluded arterial stump pressure at each hepatic arterial level using a 1.8-Fr microballoon catheter2015
Author(s)
Matsumoto T, Endo J, Hashida K, Mizukami H, Nagata J, Ishikawa H, Kojima S, Takashimizu S, Watanabe N, Hasebe T
Organizer
JSIR, ISIR & APCIO 2015
Place of Presentation
Seagaia Convention Center in Phoenix Seagaia Resor (宮崎県宮崎市)
Year and Date
2015-05-28
Related Report
Int'l Joint Research
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[Presentation] Carbon-based materials for medical applications.2015
Author(s)
Hasebe T, Matsumoto T, Yamato Y, Bito K, Maegawa S, Mine T, Hotta A, Suzuki T
Organizer
The 9th International Conference on New Diamond and Nano Carbons 2015 (NDNC2015)
Place of Presentation
静岡グランシップ (静岡県静岡市)
Year and Date
2015-05-27
Related Report
Int'l Joint Research / Invited
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