| Project/Area Number |
26861058
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Digestive surgery
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Research Collaborator |
MORI AKIKO 東北大学, 大学院消化器外科学, 大学院生
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | Fbxw7 / cholangiocarcinoma / 胆道癌 |
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| Outline of Final Research Achievements |
In order to solve the role of Ubiquitin ligase Fbxw7 and the substrates in cholangiocarcinoma, we verified the expression levels of proteins in cholaogiocarcinoma cell lines. A particular substrate was accumulated in Fbxw7 knock down cell lines. Now, we are analyzing the expression of Fbxw7 and the substrates in the surgical specimens of biliary tract cancer.
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