| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Outline of Final Research Achievements |
To improve the reliability of language mapping in brain surgery, we investigated high frequency oscillation, corticocortical evoked potential, and tractography of the arcuate fasciculus, which reflect the local cortical activity, connectivity of remote cortices, and white matter connecting language centers, respectively, and compared them with the results of electrocortical stimulation mapping, that is, the gold standard technique. The result showed the possibility that we could achieve the positive predictive value of more than 80% by combining high frequency oscillation and corticocortical evoked potential. On the other hand, the ends of the tractography were shown to be located at the periphery of the language centers.
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