| Project/Area Number |
26861180
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Shinshu University |
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Principal Investigator |
AOKI Kaoru 信州大学, 医学部, 准教授(特定雇用) (30467170)
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| Research Collaborator |
KO Yong-il 信州大学, 工学部
KIM Yoong Ahm 全南国立大学, 高分子融合素材工学部, 教授
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 肉腫 / カーボンナノチューブ / drug delivery system / 多層カーボンナノチューブ / 抗がん剤 / 塩酸ドキソルビシン / Drug delivery system / 化学療法 |
|---|
| Outline of Final Research Achievements |
Carbon nanotubes are expected as drug delivery system. To improve the effect of treatment of the bone and soft tissue sarcomas as represented by osteosarcoma, we made anticancer drug-MWCNT (multi-walled carbon nanotube) complex. We evaluated the effects of anticancer drug-MWCNT complex for osteosarcoma. Anticancer drug-MWCNT complex showed stronger antitumor effects than only anticancer drug and only MWCNTs.
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