Relationship between forced Oscillation Technique parameters and postoperative pulmonary complications.

• Project/Area Number: 26861222
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Anesthesiology
• Research Institution: Yamagata University
• Principal Investigator: Igarashi Akira 山形大学, 医学部, 助教 (40637170)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000); Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 強制オスシレーション法 / 周術期呼吸器合併症

Outline of Final Research Achievements

We prospectively investigated the association between forced Oscillation Technique (FOT) parameters and postoperative pulmonary complications. One hundred and nine patients received thoracic surgery were registered. Before operation, impedance of the respiratory system was measured using a commercially available FOT device, MostGraph-01 (Chest MI, Inc, Tokyo, Japan). Postoperative respiratory complications were observed in 17 patients. R5 and R20 were significantly lower in the subjects with postoperative complications in whole cases. In neither heart and vascular surgery nor lung and mediastinal surgery cases, there was no significant difference in the parameters obtained from FOT between the subjects with and without postoperative respiratory complications.　This study suggests that preoperative FOT parameters could not predict postoperative pulmonary complications.

Research Products

• [Journal Article] Low arterial blood oxygenation is associated with calcification of the coronary arteries in patients with chronic obstructive pulmonary disease. (2015)
  • Author(s): Inoue S, Shibata Y, Kishi H, Hasegawa H, Nitobe J, Iwayama T, Yashiro Y, Nemoto T, Sato K, Nakano H, Sato M, Nunomiya K, Aida Y, Yamauchi K, Igarashi A, Abe S, Kubota I.
  • Journal Title: Respir Investig Volume: 53 Issue: 3 Pages: 111-116
  • DOI: 10.1016/j.resinv.2015.01.002
  • Peer Reviewed
• [Journal Article] Inhibition of elastase-pulmonary emphysema in dominant-negative MafB transgenic mice. (2014)
  • Author(s): Aida Y, Shibata Y, Abe S, Inoue S, Kimura T, Igarashi A, Yamauchi K, Nunomiya K, Kishi H, Nemoto T, Sato M, Sato-Nishiwaki M, Nakano H, Sato K, Kubota I
  • Journal Title: Int J Biol Sci. Volume: 10 Issue: 8 Pages: 882-894
  • DOI: 10.7150/ijbs.8737
  • Peer Reviewed / Open Access
• [Journal Article] Association between plasma adiponectin levels and decline in forced expiratory volume in 1 s in a general Japanese population: the Takahata study. (2014)
  • Author(s): Sato K, Shibata Y, Abe S, Inoue S, Igarashi A, Yamauchi K, Aida Y, Nunomiya K, Nakano H, Sato M, Kimura T, Nemoto T, Watanabe T, Konta T, Ueno Y, Kato T, Kayama T, Kubota I.
  • Journal Title: Int J Med Sci. Volume: 11 Issue: 8 Pages: 758-764
  • DOI: 10.7150/ijms.8919
  • Peer Reviewed / Open Access
• [Journal Article] Relationship between Serum Level of Lymphatic Vessel Endothelial Hyaluronan Receptor-1 and Prognosis in Patients with Lung Cancer (2013)
  • Author(s): Nunomiya K et al.
  • Journal Title: J. Cancer Volume: 5 Issue: 3 Pages: 242-247
  • DOI: 10.7150/jca.8486
  • Peer Reviewed / Open Access