Verification of environmental, lifestyle and prenatal effects on postpartum menstrual-associated diseases

• Project/Area Number: 26861305
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Obstetrics and gynecology
• Research Institution: Tohoku University
• Principal Investigator: Watanabe Zen 東北大学, 大学病院, 助手 (40722567)
• Research Collaborator: TAKEDA Takashi 近畿大学, 東洋医学研究所, 教授 (20301260) ; METOKI Hirohito 東北医科薬科大学, 衛生学・公衆衛生学, 教授 (20580377)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000); Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
• Keywords: 月経関連疾患 / 月経困難症 / 月経前症候群 / エコチル調査 / 分娩後 / 月経痛 / 精神的ジストレス / 月経異常

Outline of Final Research Achievements

Menstrual-associated diseases, such as dysmenorrhea and premenstrual syndrome, markedly lessen the quality of women's life and have risen in recent years. And menstruation is closely related with pregnancy and delivery. From the data of JECS, maternal and child cohort study, we analyzed 2,310 pregnant women in Miyagi to verify information regarding menstrual-associated diseases after delivery.
In menstruation resuming one and a half years after delivery, pain level was associated with baseline characteristics before pregnancy,　psychological distress during pregnancy and postpartum depression and irregularity of menstruation. Premenstrual mental instability was associated with smoking and psychological distress during pregnancy. Though menstrual-associated diseases were not associated with prenatal complications and abnormal perinatal course.

Research Products

• [Journal Article] Psychological distress during pregnancy in Miyagi after the Great East Japan Earthquake: The Japan Environment and Children's Study (2016)
  • Author(s): Watanabe, Z. Iwama, N. Nishigori, H. Nishigori, T. Mizuno, S. Sakurai, K. Ishikuro, M. Obara, T. Tatsuta, N. Nishijima, I. Fujiwara, I. Nakai, K. Arima, T. Takeda, T. Sugawara, J. Kuriyama, S. Metoki, H. Yaegashi, N. Japan, Environment Children's Study, Group
  • Journal Title: Journal of affective disorders Volume: 190 Pages: 341-348
  • DOI: 10.1016/j.jad.2015.10.024
  • Peer Reviewed / Open Access
• [Presentation] Pregnant Women Had the Risk of Psychological Distress in Miyagi After the Great East Japan Earthquake: The Japan Environment and Children’s Study (JECS) (2016)
  • Author(s): Watanabe, Z. Iwama, N. Nishigori, H. Nishigori, T. Mizuno, S. Sakurai, K. Ishikuro, M. Obara, T. Tatsuta, N. Nishijima, I. Fujiwara, I. Nakai, K. Arima, T. Takeda, T. Sugawara, J. Kuriyama, S. Metoki, H. Yaegashi, N. Japan, Environment Children's Study, Group
  • Organizer: The 63rd Annual Meeting of the Society for Reproductive Investigation
  • Place of Presentation: Montreal, Canada
  • Year and Date: 2016-03-16
  • Int'l Joint Research
• [Presentation] 東日本大震災直後の被災地宮城、多くの妊婦が精神的ジストレスを抱えていた エコチル調査一次固定データより (2016)
  • Author(s): 渡邉善
  • Organizer: 第39回日本母体胎児医学会
  • Place of Presentation: ザ・セレクトン福島（福島市）