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Attempt of the HPV infected cells visualization using an in vivo fluorescent imaging

Research Project

Project/Area Number 26861321
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Obstetrics and gynecology
Research InstitutionUniversity of Fukui

Principal Investigator

SHINAGAWA AKIKO  福井大学, 学術研究院医学系部門, 助教 (90444223)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords子宮頸癌 / HPV / ICG / 蛍光イメージング / 子宮頸がん / HPV感染 / 蛍光分子イメージング
Outline of Final Research Achievements

We paid our attention to known EGFR to overexpress with the membrane protein of cervical cancer cells, and we manufactured the fluorescent imaging probe which associated anti-EGFR antibody with ICG of the fluorescence drug. Furthermore, in cervical cancer cell line (Hela), we observed it by a fluorescence microscope using a filter for ICG and confirmed that emission of light was found. We conduct the properties of matter evaluation and specific evaluation of the composition and are preparing for the animal experiment now.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (9 results)

All 2016 2014

All Presentation (7 results) Book (2 results)

  • [Presentation] HPV感染細胞を可視化する新規コルポスコピーの開発2016

    • Author(s)
      品川 明子
    • Organizer
      第58回日本婦人科腫瘍学会学術講演会
    • Place of Presentation
      米子
    • Year and Date
      2016-07-09
    • Related Report
      2015 Research-status Report
  • [Presentation] HPV感染細胞を可視化する新規コルポスコピーの開発にむけて2016

    • Author(s)
      品川 明子
    • Organizer
      第58回婦人科腫瘍学会
    • Place of Presentation
      米子コンベンションセンター(鳥取県米子市)
    • Year and Date
      2016-07-08
    • Related Report
      2016 Annual Research Report
  • [Presentation] The assessment of cervical cancer using the combination of cervical cytology and high-risk human papillomavirus testing in Fukui prefecture, Japan2016

    • Author(s)
      Tetsuji Kurokawa
    • Organizer
      The 19th International Congress of Cytology
    • Place of Presentation
      横浜
    • Year and Date
      2016-05-31
    • Related Report
      2015 Research-status Report
  • [Presentation] 福井県の子宮頸がん検診に細胞診とHPV検査の同時併用法を導入した第一報-細胞診陰性でHPV検査陽性者に着眼した取り組み-2016

    • Author(s)
      黒川 哲司
    • Organizer
      第68回日本産科婦人科学会学術講演会
    • Place of Presentation
      東京
    • Year and Date
      2016-04-23
    • Related Report
      2015 Research-status Report
  • [Presentation] 子宮頸癌における脈管侵襲陽性症例の検討2014

    • Author(s)
      品川 明子
    • Organizer
      第56回日本婦人科腫瘍学会学術講演会
    • Place of Presentation
      宇都宮市、栃木県総合文化センター
    • Year and Date
      2014-07-17 – 2014-07-19
    • Related Report
      2014 Research-status Report
  • [Presentation] 子宮頸癌の脈管侵襲陽性のみは再発リスク因子となるか-組織型の違いによる検討-2014

    • Author(s)
      品川 明子, 黒川 哲司, 井上 大輔, 太田 可奈子, 杉田 元気, 山本 真, 玉村 千代, 髙橋 仁, 服部 克成, 知野 陽子, 西島 浩二, 福田 真, 折坂 誠, 吉田 好雄
    • Organizer
      第22回福井婦人科腫瘍研究会
    • Place of Presentation
      福井市、ユアーズホテルフクイ
    • Year and Date
      2014-06-18
    • Related Report
      2014 Research-status Report
  • [Presentation] 子宮頸癌の脈管侵襲陽性のみは再発リスク因子となるか-組織型の違いによる検討-2014

    • Author(s)
      品川 明子, 黒川 哲司, 知野 陽子, 折坂 誠, 吉田 好雄
    • Organizer
      第66回日本産科婦人科学会学術講演会
    • Place of Presentation
      東京、東京国際フォーラム
    • Year and Date
      2014-04-18 – 2014-04-20
    • Related Report
      2014 Research-status Report
  • [Book] 産科と婦人科2016

    • Author(s)
      品川 明子
    • Total Pages
      3
    • Publisher
      診断と治療社
    • Related Report
      2016 Annual Research Report
  • [Book] 産科と婦人科2016

    • Author(s)
      品川 明子
    • Total Pages
      3
    • Publisher
      株式会社 診断と治療社
    • Related Report
      2015 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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