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Establishment of a new strategy of ovarian mucinous adenocarcinoma using primary culture cell mass

Research Project

Project/Area Number 26861325
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Obstetrics and gynecology
Research InstitutionOsaka University

Principal Investigator

KIMURA TOSHIHIRO  大阪大学, 医学(系)研究科(研究院), 招へい教員 (90584524)

Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords婦人科腫瘍 / 難治性卵巣悪性腫瘍 / 初代培養細胞塊 / 初代培養 / 抗癌剤感受性試験
Outline of Final Research Achievements

Epithelial ovarian malignancies, response rate to chemotherapy is considered as a high tumor. However response rate of chemotherapy has been reported to be significantly lower than other tissue types in ovarian mucinous adenocarcinoma among them. We create a primary culture cell mass of mucinous adenocarcinoma with recent new three-dimensional culture method reported in other carcinomas.It is possible to create a primary culture cell mass from the tumor tissue of a patient obtained with informed consent in writing, long-term culture in a serum-free medium, and to save.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (3 results)

All 2015 2014

All Presentation (3 results)

  • [Presentation] CTOS法による子宮頚部小細胞がん・腺がん混合腫瘍の解析2015

    • Author(s)
      久保田哲 中嶋綾 清原裕美子 遠藤洋子 奥山裕照 吉野潔 木村正 井上正宏
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Related Report
      2015 Annual Research Report
  • [Presentation] 子宮体がんの新規三次元培養CTOS法におけるmTOR阻害剤感受性の多様性2014

    • Author(s)
      清原裕美子 遠藤洋子 吉野潔 木村敏啓 上田豊 藤田征巳 木村正 井上正宏
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Related Report
      2014 Research-status Report
  • [Presentation] 子宮体癌に対するオーダーメイド分子標的治療のためのCTOSを用いた基礎的研究2014

    • Author(s)
      清原裕美子 藤田征巳 吉野潔 上田豊 木村敏啓 松崎慎哉 木村正
    • Organizer
      第66回日本産科婦人科学会学術講演会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-18 – 2014-04-20
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2017-05-10  

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