The molecular biological research of a new treatment of viral-induced inner ear dysfunction
| Project/Area Number |
26861374
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Osaka University |
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Principal Investigator |
Takimoto Yasumitsu 大阪大学, 医学(系)研究科(研究院), 特任研究員 (00624298)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 内耳障害 / 末梢前庭機能 / TLR3 / 内耳炎 / 内耳 / 前庭機能 |
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| Outline of Final Research Achievements |
We revaeled TLR3mRNA expression in the mouse cochlea, spiral ganglion, and vestibular ganglion using RT-PCR and in situ hybridization. After poly I:C intratympanic administration, the infiltration of inflammatory cells was observed in the treatment side of inner ear. We developed new evaluation system of mouse vestibular function.
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Report
(3 results)
Research Products
(1 results)
