• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Establishment of diagnostic and therapeutic methods for head and neck cancer by metabolomics

Research Project

Project/Area Number 26861382
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Otorhinolaryngology
Research InstitutionKobe University

Principal Investigator

MORIMOTO KOICHI  神戸大学, 医学研究科, 特命准教授 (90457044)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords頭頸部癌 / 低侵襲手術 / 喉頭癌 / 下咽頭癌 / 予後因子 / 脈管侵襲 / メタボローム / バイオマーカー
Outline of Final Research Achievements

For vocal cord lesions including early glottic carcinoma, vocal cord resection, which is a minimally invasive surgery combined with diagnosis and treatment, was not only acceptable for types I and II cordectomy, but also for type III cordectomy.
For hypopharyngeal cancers, transoral resection, which is minimally invasive surgery, can preserved laryngeal function in all cases and oral resection was also possible. Horizontal margin positive is a risk factor of local recurrence, but many cases are achieved to tumor control even if horizontal margin is positive. In this study, although there was no certain association between vascular invasion and recurrence pattern, it is necessary to investigate new risk factors by accumulating cases.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (11 results)

All 2017 2016 2015 2014

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (8 results) (of which Int'l Joint Research: 2 results,  Invited: 3 results)

  • [Journal Article] Treatment Outcomes of Particle Radiotherapy Using Protons or Carbon Ions as a Single-Modality Therapy for Adenoid Cystic Carcinoma of the Head and Neck2014

    • Author(s)
      Masaru Takagi,Yusuke Demizu, Naoki Hashimoto, Masayuki Mima, Kazuki Terashima, Osamu Fujii, Dongcun Jin, Yasue Niwa, Koichi Morimoto, Takashi Akagi, Takashi Daimon, Ryohei Sasaki, Yoshio Hishikawa, Mitsuyuki Abe, Masao Murakami, and Nobukazu Fuwa
    • Journal Title

      Radiotherapy and Oncology,

      Volume: 113(3) Issue: 3 Pages: 364-370

    • DOI

      10.1016/j.radonc.2014.11.031

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] 頭頸部進行がんに対する治療戦略 進行期(Stage III/IV)喉頭癌・下咽頭癌の治療戦略2014

    • Author(s)
      大月 直樹, 四宮 弘隆, 小松 弘和, 森本 浩一, 齋藤 幹, 清田 尚臣, 佐々木 良平, 丹生 健一
    • Journal Title

      頭頸部癌

      Volume: 4 Pages: 406-11

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] 当院における再発・転移頭頸部がんに対するドセタキセル・シスプラチン併用(DC)療法の遡及的解析2014

    • Author(s)
      島田 貴信, 清田 尚臣, 今村 善宣, 森本 浩一, 斉藤 幹, 西村 英輝, 大月 直樹, 佐々木 良平, 丹生 健一
    • Journal Title

      頭頸部癌

      Volume: 4 Pages: 490-6

    • NAID

      130004940782

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Presentation] Treatment outcome of transoral Resection against Hypopharyngeal Cancers2017

    • Author(s)
      Koicih Morimoto
    • Organizer
      5th Congress of Asian Society of Head and Neck Oncology
    • Place of Presentation
      Bali, Indonesia
    • Year and Date
      2017-03-23
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 早期声門癌に対する経口的CO2レーザー切除術の治療成績2016

    • Author(s)
      森本 浩一
    • Organizer
      第9回喉頭機能温存治療研究会
    • Place of Presentation
      東京都品川
    • Year and Date
      2016-11-09
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 声帯病変の取り扱い 治療方法とその時期2016

    • Author(s)
      森本 浩一
    • Organizer
      第7回北六甲耳鼻咽喉科研究会
    • Place of Presentation
      兵庫県三田市
    • Year and Date
      2016-04-16
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Treatment outcome of transoral resection using CO2 LASER against early glottic cancers2015

    • Author(s)
      Koichi Morimoto
    • Organizer
      第39回日本頭頸部癌学会(第4回アジア頭頸部癌学会)
    • Place of Presentation
      神戸
    • Year and Date
      2015-06-03 – 2015-06-06
    • Related Report
      2014 Research-status Report
  • [Presentation] Treatment outcome of transoral resection using CO2 LASER against early glottic cancers2015

    • Author(s)
      Koichi Morimoto
    • Organizer
      第4回アジア頭頸部癌学会
    • Place of Presentation
      神戸
    • Year and Date
      2015-06-03
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 当科における声帯病変に対するCO2レーザー切除症例の検討2015

    • Author(s)
      森本 浩一
    • Organizer
      第27回日本喉頭科学会
    • Place of Presentation
      東京
    • Year and Date
      2015-04-09
    • Related Report
      2015 Research-status Report 2014 Research-status Report
  • [Presentation] 喉頭蓋病変に対して経口的切除を施行した5症例の検討2014

    • Author(s)
      森本 浩一
    • Organizer
      第66回日本気管食道科学会
    • Place of Presentation
      高知
    • Year and Date
      2014-11-13 – 2014-11-14
    • Related Report
      2014 Research-status Report
  • [Presentation] Partial Laryngectomy for Radiation-Failure2014

    • Author(s)
      Koichi Morimoto
    • Organizer
      5th World Congress of IFHNOS & Annual Meeting of the AHNS
    • Place of Presentation
      New York
    • Year and Date
      2014-07-26 – 2014-07-30
    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi