Establishment of diagnostic and therapeutic methods for head and neck cancer by metabolomics
| Project/Area Number |
26861382
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Kobe University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 頭頸部癌 / 低侵襲手術 / 喉頭癌 / 下咽頭癌 / 予後因子 / 脈管侵襲 / メタボローム / バイオマーカー |
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| Outline of Final Research Achievements |
For vocal cord lesions including early glottic carcinoma, vocal cord resection, which is a minimally invasive surgery combined with diagnosis and treatment, was not only acceptable for types I and II cordectomy, but also for type III cordectomy.
For hypopharyngeal cancers, transoral resection, which is minimally invasive surgery, can preserved laryngeal function in all cases and oral resection was also possible. Horizontal margin positive is a risk factor of local recurrence, but many cases are achieved to tumor control even if horizontal margin is positive. In this study, although there was no certain association between vascular invasion and recurrence pattern, it is necessary to investigate new risk factors by accumulating cases.
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Report
(4 results)
Research Products
(11 results)
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[Journal Article] Treatment Outcomes of Particle Radiotherapy Using Protons or Carbon Ions as a Single-Modality Therapy for Adenoid Cystic Carcinoma of the Head and Neck2014
Author(s)
Masaru Takagi,Yusuke Demizu, Naoki Hashimoto, Masayuki Mima, Kazuki Terashima, Osamu Fujii, Dongcun Jin, Yasue Niwa, Koichi Morimoto, Takashi Akagi, Takashi Daimon, Ryohei Sasaki, Yoshio Hishikawa, Mitsuyuki Abe, Masao Murakami, and Nobukazu Fuwa
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Journal Title
Radiotherapy and Oncology,
Volume: 113(3)
Issue: 3
Pages: 364-370
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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