The influence of the dose of Atomic Bomb Radiation to the retinal vessel diameter, glaucoma, and age related macular degeneration

• Project/Area Number: 26861452
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Ophthalmology
• Research Institution: Hiroshima University
• Principal Investigator: Takenaka Joji 広島大学, 大学病院, 病院助教 (70526194)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2015: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000); Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
• Keywords: 被曝放射線 / 網膜血管径 / 緑内障 / 加齢黄斑変性 / 被曝線量 / 加齢黄斑変性症

Outline of Final Research Achievements

We examined whether the dose of Atomic Bomb Radiation affects the retinal vessel diameter, glaucoma, and age related macular degeneration using the fundus photograph. When the dose of radiation increases, the number of normal tension glaucoma increases, however the number of glaucoma of high intraocular pressure decreases. There were no correlation between the occurrence of age related macular degeneration and the dose of radiation.

Research Products

• [Journal Article] Exposure to Atomic Bomb Radiation and Age-Related Macular Degeneration in Later Life: The Hiroshima-Nagasaki Atomic Bomb Survivor Study (2015)
  • Author(s): Itakura K, Takahashi I, Nakashima E, Yanagi M, Kawasaki R, Neriishi K, Wang JJ, Wong TY, Hida A, Ohishi W, Kiuchi Y
  • Journal Title: Invest Ophthalmol Vis Sci. Volume: 56(9) Issue: 9 Pages: 5401-5406
  • DOI: 10.1167/iovs.15-16680
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Intraocular pressure readings obtained through soft contact lenses using four types of tonometer. (2015)
  • Author(s): Takenaka J, Kunihara E, Rimayanti U, Tanaka J, Kaneko M, Kiuchi Y.
  • Journal Title: Clin Ophthalmol. Volume: 9 Pages: 1875-1881
  • DOI: 10.2147/opth.s84953
  • Peer Reviewed
• [Journal Article] Is the association between smoking and the retinal venular diameter reversible following smoking cessation? (2014)
  • Author(s): Yanagi M, Misumi M, Kawasaki R, Takahashi I, Itakura K, Fujiwara S, Akahoshi M, Neriishi K, Wong TY, Kiuchi Y.
  • Journal Title: Invest Ophthalmol Vis Sci. Volume: 55 Issue: 1 Pages: 405-411
  • DOI: 10.1167/iovs.13-12512
  • Peer Reviewed