The possibility of early axonal functional recovery using the squid giant axon

• Project/Area Number: 26861494
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Plastic surgery
• Research Institution: The University of Tokyo
• Principal Investigator: Narushima Mitsunaga 東京大学, 医学部附属病院, 講師 (80431873)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000); Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: 神経 / 軸索 / イカ / 変性 / 巨大軸索 / 再生

Outline of Final Research Achievements

We controlled squid body under a low temperature. Aster established giant axon in vivo model, we investigated and invented new dye injection method to giant axon.We performed the study about clamp of giant axon. We confirmed that axonal recover was occurred up to 30 minutes after clamping.

Research Products

• [Journal Article] いかをいかにいかすか (2015)
  • Author(s): 成島三長
  • Journal Title: Toba super Aquarium (TSA) Volume: 67 Pages: 14-15
• [Presentation] Local anesthesia and analgesia in Cephalopods: a model of nociceptive behavior using stellate ganglion and nerve blocks (2015)
  • Author(s): Mitsunaga Narushima
  • Organizer: Cephalopod International Advisory Council
  • Place of Presentation: 函館
  • Year and Date: 2015-11-09
  • Int'l Joint Research
• [Presentation] イカ巨大軸索in vivo実験モデルを用いた軸索内輸送の可視化 (2015)
  • Author(s): 成島三長
  • Organizer: 日本形成外科学会基礎学術集会
  • Place of Presentation: 盛岡
  • Year and Date: 2015-10-08
• [Presentation] 各種血管付き神経移植による再建法と実験研究 (2015)
  • Author(s): 成島三長
  • Organizer: 第26回日本末梢神経学会学術集会
  • Place of Presentation: 松本
  • Year and Date: 2015-09-18
• [Presentation] 気づかないいかに気づくか (2014)
  • Author(s): 成島三長
  • Organizer: 形成外科学会基礎学術集会
  • Place of Presentation: 松本
  • Year and Date: 2014-10-09
• [Presentation] 侵害受容実験モデルと神経節ブロック法の開発 (2014)
  • Author(s): 成島三長
  • Organizer: 第25回日本末梢神経学会
  • Place of Presentation: 京都
  • Year and Date: 2014-08-29 – 2014-08-30