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Indocyanine green fluorescence lymphography with exercise loading for screening of lymphedema

Research Project

Project/Area Number 26861502
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Plastic surgery
Research InstitutionOkayama University

Principal Investigator

Matsumoto Kumiko  岡山大学, 大学病院, 医員 (20616049)

Research Collaborator KIMATA YOSHIHIRO  岡山大学, 大学院医歯薬学総合研究科, 教授 (50392345)
SHINAOKA AKIRA  岡山大学, 大学院医歯薬学総合研究科, 助教 (90724500)
YAMADA KIYOSHI  岡山大学, 大学病院, 助教 (10319965)
Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywordsリンパ浮腫 / ICGリンパ管造影 / 運動負荷 / 浮腫 / リンパ管造影検査 / ICG造影検査 / ICG蛍光造影 / ICG
Outline of Final Research Achievements

Indocyanine green fluorescence lymphography (ICG) is widely used to observe a function and the course of the lymphatic vessels for lymphedema diagnosis.
There is no report about exercise loaded ICG lymphography. In this study, we aimed for shortening the exercise time and establishing the standard protocol of ICG lymphography, we observed detail image of exercise loaded ICG and examined the change of finding over time at each stage of International Society of lymphedema (ISL) classification. The rise speed of indocyanine green tended to be slow as the stage got worse. In all stages after 20 minutes exercise, DB appearance rate didn’t change any more. The suitable exercise duration after ICG injection is 20 minutes. ICGLG is useful for screening for lymphedema. In the future, we are planning to standardize the protocols and also plan to create simple evaluation methods.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (13 results)

All 2017 2016 2015 2014

All Journal Article (5 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 5 results,  Acknowledgement Compliant: 1 results) Presentation (8 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] Detailed Examination of the Characteristics and Treatment in a Series of 33 Idiopathic Lymphedema Patients.2017

    • Author(s)
      Onoda S, Yamada K, Matsumoto K, Kimata Y.
    • Journal Title

      Jounal of Reconstructive Microsurgery

      Volume: 33-1 Issue: 01 Pages: 19-25

    • DOI

      10.1055/s-0036-1586257

    • Related Report
      2017 Annual Research Report 2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Histologic Evaluation of Lymphaticovenular Anastomosis Outcomes in the Rat Experimental Model: Comparison of Cases with Patency and Obstruction.2016

    • Author(s)
      Onoda S, Kimata Y, Matsumoto K, Yamada K, Tokuyama E, Sugiyama N.
    • Journal Title

      Plast Reconstr Surg.

      Volume: 137(1) Issue: 1 Pages: 83e-91e

    • DOI

      10.1097/prs.0000000000001884

    • NAID

      120006318837

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Analysis of 10-Year Training Results of Medical Students Using the Microvascular Research Center Training Program.2016

    • Author(s)
      Onoda S, Kimata Y, Sugiyama N, Tokuyama E, Matsumoto K, Ota T, Thuzar M.
    • Journal Title

      J Reconstr Microsurg.

      Volume: e-pub Issue: 05 Pages: 336-341

    • DOI

      10.1055/s-0035-1568884

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] A Novel Lymphaticovenular Anastomosis Rat2016

    • Author(s)
      Onoda S, Kimata Y, Matsumoto K.
    • Journal Title

      Ann Plast Surg.

      Volume: 76(3): Issue: 3 Pages: 332-5

    • DOI

      10.1097/sap.0000000000000571

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] リンパ浮腫保存治療の発症要因別治療効果2014

    • Author(s)
      三宅一正、丸濱恵、本多文江、亀山真吾、小野敦、山田潔、 松本久美子
    • Journal Title

      リンパ学

      Volume: 37-2 Pages: 62-65

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Presentation] リンパ浮腫に対するLiposuction + Distal LVA 機能回復と整容性の改善2017

    • Author(s)
      山田潔、品岡玲、松本久美子、小野田聡、杉山成史、木股敬裕
    • Organizer
      第60回日本形成外科学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 我が国の診療の現状と課題 外来設立・入院・緩和・地域連携の在り方を探る~リンパ浮腫進行例に対する脂肪吸引術2017

    • Author(s)
      山田潔、品岡玲、越宗靖二郎、松本久美子、木股敬裕、本田雅子、三宅麻希、三宅一正、丸濱恵
    • Organizer
      第2回リンパ浮腫治療学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Standardizing a protocol of indocyanine green fluorescence lymphography (ICG-LG) with the exercise for lower extremity lymphedema2017

    • Author(s)
      Seijiro Koshimune, Kumiko Matsumoto, Akira Shinaoka, Kiyoshi Yamada, Yoshihiro Kimata
    • Organizer
      26th World congress of Lymphology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Suction assisted lipectomy plus distal LVA for advanced stage lower extremity lymphedema2017

    • Author(s)
      Kiyoshi Yamada, Akira Shinaoka, Kumiko Matsumoto, Satoshi Onoda, Narushi Sugiyama, Yoshihiro Kimata
    • Organizer
      26th World congress of Lymphology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ICGリンパ管造影における high flowパターンの リンパ管の検討2016

    • Author(s)
      木下雅人、山田潔、品岡玲、松本久美子、木股敬裕
    • Organizer
      第43回日本マイクロサージャリー学会学術集会
    • Place of Presentation
      広島
    • Year and Date
      2016-11-17
    • Related Report
      2016 Research-status Report
  • [Presentation] リンパ浮腫診断における運動負荷ICG蛍光リンパ管造影検査2015

    • Author(s)
      松本 久美子
    • Organizer
      蛍光Navigation Surgery研究会
    • Place of Presentation
      浜松
    • Year and Date
      2015-10-17
    • Related Report
      2015 Research-status Report
  • [Presentation] リンパ流速を考慮したリンパ管再静脈吻合術に関して2015

    • Author(s)
      品岡玲、山田潔、松本久美子ほか
    • Organizer
      第39回日本リンパ学会総会
    • Place of Presentation
      東京
    • Year and Date
      2015-03-27 – 2015-03-28
    • Related Report
      2014 Research-status Report
  • [Presentation] LVAと術前後理学療法について2014

    • Author(s)
      山田潔、木股敬裕、杉山成史、松本久美子、品岡玲
    • Organizer
      第57回日本形成外科学会学術集会
    • Place of Presentation
      長崎
    • Year and Date
      2014-04-09 – 2014-04-11
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2019-03-29  

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