The development of the reflection type quantitative ultrasound bone intensity measurement device for jawbones

• Project/Area Number: 26861581
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Pathobiological dentistry/Dental radiology
• Research Institution: Kanagawa Dental College
• Principal Investigator: Kozai Yusuke 神奈川歯科大学, 歯学研究科(研究院), 講師 (80550855)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000); Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: 骨粗鬆症 / 骨密度 / 骨質 / 超音波 / 骨強度 / 顎骨

Outline of Final Research Achievements

We developed new reflection type quantitative ultrasound bone density measuring apparatus and tested the measurement accuracy. We planned the application of the device to the site which we were hard to measure in before. As a result, it was confirmed that we could infer the bone density of target bones by measuring SOS with the reflection type quantitative ultrasound bone density measuring apparatus that we developed newly. Whereas it was found in the reflection wave SOS of this device that the estimate of the bone substance was difficult.

Research Products

• [Journal Article] Nanosized hｙdroxyapatite coating on PEEK implants enhances early bone formation: A histological and three-dimensional investigation in rabbit bone (2015)
  • Author(s): Johansson P, Jimbo R, Kozai Y, Sakurai T, Kjellin P, Currie F, Wennerberg A
  • Journal Title: Materials Volume: 8 Issue: 7 Pages: 3815-30
  • DOI: 10.3390/ma8073815
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Inhibitory effect of collagen-mineral complex on deterioration of bone mass and quality in ovariectomized mice (2014)
  • Author(s): Kozai Y, Iino M, Innami H, Kawamata R, Wakao H, Sakurai T
  • Journal Title: Oral Radiology Volume: 30 Issue: 3 Pages: 203-211
  • DOI: 10.1007/s11282-013-0160-2
  • Peer Reviewed
• [Journal Article] Guided bone augmentation using a ceramic space-maintaining device. (2014)
  • Author(s): Anderud J, Jimbo R, Abrahamsson P, Isaksson SG, Adlfsson E, Malmstrom J, Kozai Y, Hallmer F, Wennerberg A
  • Journal Title: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Volume: 118 Issue: 5 Pages: 532-538
  • DOI: 10.1016/j.oooo.2014.06.011
  • Peer Reviewed / Open Access
• [Presentation] 骨粗鬆症モデルマウスを用いたパプリカ色素の骨粗鬆症予防効果に関する基礎的研究 (2015)
  • Author(s): 香西雄介、印南 永、谷口紀江、川股亮太、若尾博美、櫻井 孝
  • Organizer: 日本歯科放射線学会 第56回総会・学術大会
  • Place of Presentation: 仙台市
  • Year and Date: 2015-06-06
• [Presentation] 超音波の反射波を利用した骨密度測定の測定精度に関する検討 (2014)
  • Author(s): 香西雄介，印南永，川股亮太，櫻井孝
  • Organizer: 日本歯科放射線学会第55回総会・学術大会
  • Place of Presentation: 東京
  • Year and Date: 2014-06-06 – 2014-06-08
• [Remarks] 簡易的反射型超音波骨密度測定システムの紹介
  • URL: http://www.labs.kdu.ac.jp/radiol/qus.html