Cytotoxic effects of hydrogen peroxide on human gingival fibroblastsfor clinical cases

Research Project

Project/Area Number	26861604
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Conservative dentistry
Research Institution	Showa University
Principal Investigator	FURUKAWA MASAE 昭和大学, 歯学部, 兼任講師 (90439456)
Project Period (FY)	2014-04-01 – 2017-03-31
Project Status	Completed (Fiscal Year 2016)
Budget Amount *help	¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000) Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000) Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords	オフィスブリーチ / 歯肉為害性 / side effects / gingival irritation / hydrogen peroxide / 漂白 / 歯肉細胞 / 為害性 / 歯肉 / 歯肉線維芽細胞 / 過酸化水素
Outline of Final Research Achievements	Office bleach is a popular treatment in modern aestheric dentistry. However, bleaching agents are sometimes accidentally adhered to gingiva and peripheral tissues even by well-trained operators, which leads to transient pain and whitish change of gingiva. Regarding the influence of this bleaching agent on gingiva, we concluded that it can be prevented by clarifying that it is an inflammatory reaction and applying vitamin E. Thin time I aimed to make it easy and safe for anyone in clinical practice, but I could not achieve it.

Report

(4 results)