Comprehensive analysis of bacterial flora around dental implants by Next Generation Sequencer and development of antibacterial therapy.
Project/Area Number |
26861637
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Prosthodontics/ Dental materials science and
|
Research Institution | Okayama University |
Principal Investigator |
Ono Aya 岡山大学, 大学病院, 助教 (20584626)
|
Research Collaborator |
窪木 拓男 (00225195)
大野 充昭 (60613156)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
Keywords | 口腔インプラント / インプラント周囲炎 / 細菌叢 / 次世代シークエンサー / メタゲノム解析 / 歯学 / 臨床疫学 |
Outline of Final Research Achievements |
It is still unclear the constitution of bacteria in peri-implantitis. We analyzed the bacterial flora of the exudate around dental implant body suffered from peri-implantitis by NGS. The experimental results were revealed that there are differences between individuals in the bacterial flora, and the peri-implantitis and the periodontal disease were similar bacterial flora and the healthy dental implants and the healthy tooth were also similar in the bacterial flora.
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Report
(4 results)
Research Products
(2 results)