Reaction of brain redox on oral rehabilitation in cerebral infarction animal model under percutaneous endoscopic gastrostomy placement
| Project/Area Number |
26861649
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Prosthodontics/ Dental materials science and
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| Research Institution | Health Sciences University of Hokkaido |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 脳梗塞 / 抗酸化能 / 舌運動 / マイクロダイアリシス / 尿酸 / 咀嚼 / 海馬 / 経管栄養摂取 / 咬合 |
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| Outline of Final Research Achievements |
The purpose of this study was to investigate whether the oral rehabilitation contributes the functional recovery from stroke-induced compromised antioxidant ability in cerebral ischemic rat model. The measurement of the antioxidant ability in the CA1 region of the hippocampus was performed by using the HPLC-ECD.
An antioxidant ability was increased at the stimuli by not tubal feeding, but oral nutrition intake. These results suggested that the nutritional support through a tube inserted into the stomach without oral intake may have a negative effect on recovery from cerebral infarction.
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Report
(4 results)
Research Products
(6 results)
