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Restoring occlusion in rats with missing molar teeth stabilizes their emotions

Research Project

Project/Area Number 26861666
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Prosthodontics/ Dental materials science and
Research InstitutionOsaka Dental University

Principal Investigator

YAMAMOTO Satsuki  大阪歯科大学, 歯学部, 講師 (20399091)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywordsホールボード試験 / 情動行動 / 不安 / 咬合障害 / 情動 / ラット / 咬合
Outline of Final Research Achievements

To clarify the effects of altered occlusion on psychological stress, I observed emotional behavior changes in rats that experienced occlusal interference. Nine male Sprague-Dawley rats were randomly assigned to a control group, an interference group, or a temporary interference group, each with 3 rats. The interference group rats were given aluminum laminates on the occlusal surface of their teeth, the temporary interference group rats were given temporary laminates for 30 minutes, and the control group rats underwent a sham operation. I recorded the frequency and duration of head-dipping, total activity time, and movement distance, all of which decrease when rats are depressed.
The rats with disrupted occlusion exhibited lower head-dipping frequencies than the control group and temporary interference group rats. This suggests that occlusal interference causes psychological stress in rats.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (1 results)

All 2016

All Journal Article (1 results) (of which Peer Reviewed: 1 results)

  • [Journal Article] Influence of titanium surface topography on in vitro differentiation of bone marrow mesenchymal stem cells into osteoblasts2016

    • Author(s)
      Komasa S, Miyake A, Fujio M, Nishizaki M, Taguchi Y, Kusumoto T, Okajima Y, Yoshioka Y, Yoshimine S, Yamamoto S, Onchi Y, Kon-I H, Nishizaki H, Okazaki J
    • Journal Title

      バイオインテグレーション学会雑誌

      Volume: 6 Pages: 17-26

    • NAID

      40021072848

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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