The development of new methods of bone regeneration utilizing differentiation plasticity.
| Project/Area Number |
26861669
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 軟骨細胞 / 分化可塑性 / 培養再生骨 / 培養軟骨細胞 / 骨化 / 軟骨分化可塑性 / 分化誘導 |
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| Outline of Final Research Achievements |
We developed and examined the new bone regeneration process using differentiation plasticity of chondrocytes.It can also be expected as a cell source of bone by ossification of chondrocyte.We established a bone reproduction technology having enough bone masses using chondrocytes as a cell source of bone.In the first year, We confirmed the differentiation plasticity in the culture chondrocyte and examined a condition of the culture reproduction osseous tissue manufacture.After the next fiscal year,We established a optimal condition by nude rat subcutaneous implantation and the skull defect model.
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Report
(3 results)
Research Products
(1 results)
