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The optimal setting of LIPUS after maxillary sinus augmentation

Research Project

Project/Area Number 26861681
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Dental engineering/Regenerative dentistry
Research InstitutionHealth Sciences University of Hokkaido

Principal Investigator

TAKEBE Hiroaki  北海道医療大学, 歯学部, 助教 (40638293)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords低出力パルス超音波刺激 / 動物実験 / LIPUS / 細胞培養 / 上顎洞底挙上術 / 骨増生 / 超音波パルス刺激
Outline of Final Research Achievements

Low-intensity pulsed ultrasound stimulation (LIPUS) is used in orthopedics as a supplementary therapy to promote healing of pathological and traumatic fractures, and it has also been used in dental implant surgery. Little research exists on the effects of ultrasound on maxillary sinus augmentation, and the mechanism involved is unclear. The results suggest that clinical application of LIPUS for sinus augmentation may promote new bone formation and that LIPUS enhances cell proliferation related to newly formed bone at 1 week following maxillary sinus augmentation and that this effect is greater at a frequency of 1 MHz than at 3 MHz.This research suggests that LIPUS may affects the distance from osteoblastic cell to the LIPUS probe.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (4 results)

All 2016 2014

All Journal Article (1 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (3 results)

  • [Journal Article] Effects of Low-intensity Pulsed Ultrasound on Healing after Maxillary Sinus Augmentation in Rabbits2016

    • Author(s)
      Hiroaki Takebe, Yasuhiro Nakanishi, Yukito Hirose, Pao-Li Wang, Kazuharu Irie, Morio Ochi
    • Journal Title

      Journal of Hard Tissue Biology

      Volume: 25 Issue: 4 Pages: 395-402

    • DOI

      10.2485/jhtb.25.395

    • NAID

      130005249134

    • ISSN
      1341-7649, 1880-828X
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Presentation] 低出力パルス超音波の刺激到達距離が骨芽細胞分化に与える影響2016

    • Author(s)
      建部廣明,仲西康裕,廣瀬由紀人,荒川俊哉,入江一元,越智守生
    • Organizer
      日本口腔インプラント学会
    • Place of Presentation
      名古屋国際会議場(愛知県、名古屋市)
    • Year and Date
      2016-09-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] 低出力パルス超音波による骨形成促進効果の至適条件の検索2016

    • Author(s)
      建部廣明、仲西康裕、廣瀬由紀人、荒川俊哉、入江一元、越智守生
    • Organizer
      日本口腔インプラント学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2016-09-16
    • Related Report
      2015 Research-status Report
  • [Presentation] Effects of Low intensity pulsed ultrasound stimulation on bone formation after sinus augmentation2014

    • Author(s)
      Hiroaki Takebe
    • Organizer
      Asian Academy of Osseointegration
    • Place of Presentation
      札幌教育文化会館(北海道札幌市)
    • Year and Date
      2014-07-05
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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