Elucidation of mechanisms maintaining and regenerating secretory function of water in salivary glands that occurs mastication
| Project/Area Number |
26861774
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Orthodontics/Pediatric dentistry
|
|---|
| Research Institution | Tokyo Medical and Dental University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
|---|
| Keywords | 唾液腺 / AQP5 / 咀嚼 / アクアポリン |
|---|
| Outline of Final Research Achievements |
We investigated alteration of water secretory function in salivery glands that occurs change and recovery of mastication. In this study, we elucidated that AQP5 was detected on the apical membrane of acinar cells, inter cellular secretory canaliculi of acinar cell in sabmandibular salivary gland in the masticatory hypofunciton group, but the staining appeared to be less prominent than that in the control group. In the masticatory recovery group, expression of AQP5 was observed on that area again. These result.
|
Report
(4 results)
Research Products
(7 results)
