| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
Mounting evidence from epidemiological studies indicates the association between periodontal disease and metabolic syndrome. Gender difference in this association has been reported, and is expected to be related to antioxidative factor. This study investigated whether antioxidative factor such as Paraoxonase1 (PON1) was associated with in periodontal disease and metabolic syndrome in males and females.
This study included 138 subjects who received oral examination in 2009 and 2012. Males who developed periodontal disease in 3 years were likely to have metabolic syndrome. In males, PON1 was associated with metabolic syndrome, and but not with periodontal disease. Females did not have the association among periodontal disease, metabolic syndrome, and PON1.
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