Randomized control trial of effect of aromatherapy to prevent hypothyroidism during I-131 ablation in patients with differentiated thyroid cancer.

Research Project

Project/Area Number	26861880
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Clinical nursing
Research Institution	Asahikawa Medical College
Principal Investigator	NAKAYAMA MICHIHIRO 旭川医科大学, 医学部, 助教 (00516776)
Project Period (FY)	2014-04-01 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000) Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000) Fiscal Year 2014: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords	甲状腺癌 / アロマセラピー / 放射性ヨード / 内用療法 / アミラーゼ / ストレス
Outline of Final Research Achievements	We investigated the physiological and psychological effects of aromatherapy in patients undergoing radioactive iodine (I-131) ablation with differentiated thyroid cancer. The subjects were 71 patients with DTC. They were divided into aromatherapy group and a control group. Some physiological and psychological indices were measured before and during I-131 ablation. Physiological effect was measured using salivary amylase activity, Saxon test, and salivary gland scintigraphy. Psychological effect was measured using the State Trait Anxiety Inventory-Form JYZ (STAI). The aromatic effects may alleviate negative emotional stress, which, at least in part, would contribute to the suppression of sympathetic nervous system activity.