| Budget Amount *help |
¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Outline of Final Research Achievements |
To find evidence related to dysphagia intervention, this study aimed to clarify the heritability of dysphagia. Participants were adult twins. In total, 28 twin pairs (n=56) participated; 86% were monozygotic, and 77% were females. The mean of age was 58.6 (SD=11.7) years. By univariate genetic analyses, we calculated the heritability of the risk and prevalence of dysphagia. The heritability of dysphagia risk was more influenced by additive genetic factor, whereas that of dysphagia prevalence was more affected by environmental factor.
By co-twin study, intake of pepper and high temperature food were significantly associated with low dysphagia risk in individual model. However, in co-twin model, these association were not significant. Thus, the result suggested that there might be common genetic effects between food preference and dysphagia.
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