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Multidimensional analysis with MRI on mechanisms of cognitive behavioral therapy for obsession

Research Project

Project/Area Number 26870100
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Clinical psychology
Psychiatric science
Research InstitutionChiba University

Principal Investigator

Sutoh Chihiro  千葉大学, 大学院医学研究院, 助教 (30612650)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords磁気共鳴画像法 / 機能的磁気共鳴画像法 / 認知行動療法 / 心理療法 / 認知再構成 / 強迫症
Outline of Final Research Achievements

To clarify the neural mechanisms of cognitive restructuring, a fundamental method within cognitive behavioural therapy, we designed a unique task that replicated psychotherapy during a brain scan. The brain activities and anatomical information of healthy participants were analysed using magnetic resonance imaging. During the brain scan, participants underwent Socratic questioning aimed at cognitive restructuring regarding the necessity of handwashing after using the restroom. The behavioural result indicated that the questioning effectively decreased the participants' degree of belief that they must wash their hands. Alterations in the degree of belief showed a positive correlation with activity in the left posterior parietal cortex and positive correlations with the white matter integrity in the left hemisphere. The involvement of these brain regions in planning, decision-making, and conceptualization may play a pivotal role in cognitive restructuring.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (6 results)

All 2015 2014 Other

All Journal Article (2 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (2 results) (of which Int'l Joint Research: 1 results) Remarks (2 results)

  • [Journal Article] Transient contribution of left posterior parietal cortex to cognitive restructuring2015

    • Author(s)
      Sutoh C, Matsuzawa D, Hirano Y, Yamada M, Nagaoka S, Chakraborty S, Ishii D, Matsuda S, Tomizawa H, Ito H, Tsuji H, Obata T, Shimizu E.
    • Journal Title

      Sci Rep

      Volume: 5 Issue: 1 Pages: 9199-9199

    • DOI

      10.1038/srep09199

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] ニューロサイエンスと認知行動療法の統合2014

    • Author(s)
      清水栄司,最上多美子,守口善也,今井正司,須藤千尋
    • Journal Title

      認知療法研究

      Volume: 7 Pages: 144-153

    • Related Report
      2014 Research-status Report
  • [Presentation] Neural basis of the Socratic questioning as a therapeutic method for cognitive restructuring2015

    • Author(s)
      Chihiro Sutoh
    • Organizer
      WPA Regional Congress Osaka Japan 2015
    • Place of Presentation
      大阪国際会議場(大阪府大阪市)
    • Year and Date
      2015-06-04
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Functional and structural brain representation of cognitive restructuring2014

    • Author(s)
      ・Chihiro Sutoh, Daisuke Matsuzawa, Yoshiyuki Hirano, Makiko Yamada, Sawako Nagaoka, Daisuke Ishii, Shingo Matsuda, Haruna Tomizawa, Hiroshi Ito, Hiroshi Tsuji, Takayuki Obata, Eiji Shimizu
    • Organizer
      44th EABCT Congress
    • Place of Presentation
      The Hague (Nederlands)
    • Year and Date
      2014-09-10 – 2014-09-13
    • Related Report
      2014 Research-status Report
  • [Remarks] 認知行動療法による信念の変化を脳画像解析で確認

    • URL

      http://www.chiba-u.ac.jp/general/publicity/press/files/2015/20150318.pdf

    • Related Report
      2016 Annual Research Report
  • [Remarks] 認知行動療法による信念の変化を脳画像解析で確認

    • URL

      http://www.chiba-u.ac.jp/general/publicity/press/pdf/2015/20150318.pdf

    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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