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Longitudinal study of progression and improvement factors of chronic kidney disease using health checkup cohort

Research Project

Project/Area Number 26870218
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Hygiene and public health
Epidemiology and preventive medicine
Research InstitutionKanazawa University

Principal Investigator

Toyama Tadashi  金沢大学, 附属病院, 特任助教 (50624871)

Research Collaborator WADA Takashi  金沢大学, 医学系, 教授 (40334784)
FURUICHI Kengo  金沢大学, 附属病院, 准教授 (50432125)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords臨床疫学 / 尿酸 / 慢性腎臓病 / 高尿酸血症 / 生活習慣病 / 予防医学
Outline of Final Research Achievements

A longitudinal study was conducted for those who received a medical examination from 1998 to 2007 on the relationships between serum uric acid (SUA) and the development of chronic kidney disease (CKD). In a study with eGFR less than 60 mL /min/1.73m2 as an outcome, the risk was high in the group with SUA 6 mg/dL or higher, compared to the group with SUA 4 to 4.9 mg/dL in men. The same study was done for women, but no obvious trend was observed. On the other hand, in a study with proteinuria 1+ or more as an outcome, the risk is higher in women with SUA 6 mg/dL or higher than the group with SUA less than 4 mg/dL, and an obvious trend was not observed in men.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (8 results)

All 2016 2015 2014

All Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (4 results) (of which Int'l Joint Research: 3 results) Book (2 results)

  • [Journal Article] Relationship between Serum Uric Acid Levels and Chronic Kidney Disease in a Japanese Cohort with Normal or Mildly Reduced Kidney Function.2015

    • Author(s)
      Toyama T, Furuichi K, Shimizu M, Hara A, Iwata Y, Sakai N, Perkovic V, Kobayashi M, Mano T, Kaneko S, Wada T.
    • Journal Title

      PLoS One.

      Volume: 10 Issue: 9 Pages: e0137449-e0137449

    • DOI

      10.1371/journal.pone.0137449

    • NAID

      120005680030

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Treatment and impact of dyslipidemia in diabetic nephropathy.2014

    • Author(s)
      Toyama T, Shimizu M, Furuichi K, Kaneko S, Wada T.
    • Journal Title

      Clin Exp Nephrol

      Volume: - Issue: 2 Pages: 201-5

    • DOI

      10.1007/s10157-013-0898-1

    • NAID

      120005349173

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Hyperuricemia As A Risk Factor For Proteinuria In Japanese General Population2016

    • Author(s)
      Tadashi Toyama, Shinji Kitajima, Akinori Hara, Yasunori Iwata, Norihiko Sakai, Miho Shimizu, Kengo Furuichi, Takashi Wada
    • Organizer
      ASN Kidney Week 2016
    • Place of Presentation
      シカゴ(アメリカ)
    • Year and Date
      2016-11-18
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] HYPERURICEMIA AS A RISK FACTOR FOR THE DEVELOPMENT OF PROTEINURIA: AN ANALYSIS OF GENERAL POPULATON COHORT.2016

    • Author(s)
      Tadashi Toyama, Kengo Furuichi, Shinji Kitajima, Akinori Hara, Yasunori Iwata, Norihiko Sakai, Miho Shimizu, Takashi Wada
    • Organizer
      APCN/ANZSN 2016
    • Place of Presentation
      パース(オーストラリア)
    • Year and Date
      2016-09-18
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 一般住民における蛋白尿発症のリスク因子としての高尿酸血症2016

    • Author(s)
      遠山直志,北島信治,原章規,岩田恭宜,坂井宣彦,清水美保,古市賢吾,和田隆志
    • Organizer
      第59回 日本腎臓学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2016-06-19
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 一般住民における蛋白尿発症のリスク因子としての高尿酸血症2016

    • Author(s)
      遠山直志、北島信治、原章規、岩田恭宜、坂井宣彦、清水美保、古市賢吾、和田隆志
    • Organizer
      日本腎臓学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-06-19
    • Related Report
      2015 Research-status Report
  • [Book] 尿酸と血糖2016年4月号 Vol.2 no.22016

    • Author(s)
      遠山直志、和田隆志
    • Total Pages
      56
    • Publisher
      先端医学社
    • Related Report
      2015 Research-status Report
  • [Book] C.全身性疾患と腎障害 1.糖尿病性腎症における脂質代謝異常 Annual Review 2015腎臓2015

    • Author(s)
      遠山直志,和田隆志
    • Total Pages
      3
    • Publisher
      中外医学社
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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