| Project/Area Number |
26870339
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
Medical Physics and Radiological Technology
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| Research Institution | Osaka University |
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Principal Investigator |
Saito Shigeyoshi 大阪大学, 医学(系)研究科(研究院), 助教 (40583068)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 生体イメージング / 磁気共鳴医学 / MRI / 高磁場MRI / 転移性脳腫瘍 / 生体イメージング技術 |
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| Outline of Final Research Achievements |
The purpose of this study is in-vivo imaging of ｐroliferation, invasion and metastasis of brain metastatictumor model. A brain metastatic tumor model were established from breast cancer tumor. At each stage of growth, migration, invasion and metastasis from the primary tumor, the in-vivo imaging such as 11.7T-MRI, 1.5T-MRI, Micro-CT and fluorescence imaging for non-invasive evaluation. In addition, the factors involved in the growth and metastasis of tumor cells ere claryfied using the molecular biological techniques such as PCR, western blot, flow cytometry and immunohistochemical staining. We established non-invasive evaluation of brain metastatictumor model by in-vivo imaging .
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