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The effects of an underwater exercise program on cardiorenal syndrome among diabetes patients

Research Project

Project/Area Number 26870361
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Rehabilitation science/Welfare engineering
Applied health science
Research InstitutionKobe University

Principal Investigator

Ono Kumiko  神戸大学, 保健学研究科, 助教 (30467667)

Research Collaborator MICHIUE Kana  
OHASHI Keita  
Project Period (FY) 2014-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords水中運動 / 糖尿病 / 腎症 / 尿中アルブミン排泄量 / 尿中L-FABP / 心腎連関 / 2型糖尿病 / 水中トレッドミル歩行 / 二重積
Outline of Final Research Achievements

The purpose of this study was to clarify the effects of underwater treadmill walking on cardiorenal syndrome among type 2 diabetes patients. Type 2 diabetes patients participated voluntarily in this study. They walked on the treadmill belt at 40% VO2 max for 30 min twice a week for 4 weeks. Two conditions were set: exercise in the water and exercise on the ground. This was a randomized, crossover trial. Urine was collected before and after the 4-week walking program intervention in each condition. And then we examine the urinary albumin excretion and Liver-type fatty acid binding protein, and double product at 40%of VO2max walking. Among the patients which stage of diabetic renal disease has progressed, it is suggested that underwater exercise is recommended when treadmill walking at the 40% of VO2max is the exercise program.

Academic Significance and Societal Importance of the Research Achievements

これまで明らかにされている水中運動の利点として、浮力による荷重関節の負担軽減ならびに心臓副交感神経系活動の亢進に関するものが多くを占めていた。また、腎臓に及ぼす運動負荷の影響については、負の要素が強調されてきた。一方で、近年では運動制限をするのではなく、身体活動量を保つことが腎疾患患者において良い影響を及ぼすことが明らかにされてきている。その流れの中で、本研究において水中トレッドミルを用いた運動介入が、腎機能および心負担の観点から糖尿病腎症の病期が進行した患者に対して推奨される可能性を示したことは、腎機能が低下した患者にとって運動選択の幅を広げ、腎保護にもつながる基礎的な研究となりえた。

Report

(6 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (6 results)

All 2018 2017 2016 2014

All Presentation (6 results) (of which Int'l Joint Research: 2 results)

  • [Presentation] 2型糖尿病患者に対する4週間の水中歩行運動が尿中アルブミン排泄量に及ぼす影響2018

    • Author(s)
      小野くみ子、道上可奈、大橋啓太、渡瀬涼、廣田勇士、岡田裕子、坂口一彦、石川朗
    • Organizer
      第55回日本糖尿病学会近畿地方会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Effects of 4-week underwater treadmill walking on liver-type fatty acid binding protein (L-FABP) among type 2 diabetes patients with renal dysfunction2018

    • Author(s)
      Ono K,Michiue K, Ohashi K,Watase R,Hirota Y, Okada Y, Sakaguchi K, Ishikawa A
    • Organizer
      12th IDF-WPR Congress & 10th AASD Scientific Meeting
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 2型糖尿病患者における水中および陸上トレッドミル歩行が腎機能および心負担に及ぼす影響2017

    • Author(s)
      小野くみ子,道上可奈,大橋啓太,鳥澤幸太郎,廣田勇士,岡田裕子,坂口一彦,石川朗
    • Organizer
      第79回日本体力医学会中国四国地方会
    • Related Report
      2017 Research-status Report
  • [Presentation] Effects of underwater treadmill walking on urinary electrolytes among type 2 diabetes patients2016

    • Author(s)
      Kumiko ONO, Kana MICHIUE, Tatsuya SUGIMOTO, Kazuya SUGIYAMA, Kumi TAKAMORI, Yushi HIROTA, Kazuhiko SAKAGUCHI, Akira ISHIKAWA
    • Organizer
      The 7th Asia Conference on Kinesiology
    • Place of Presentation
      Songdo Campus, Incheon National University, Incheon, Korea
    • Year and Date
      2016-11-11
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 水中トレッドミル歩行運動が2型糖尿病患者の心拍数、血圧および尿中アルブミン排泄量に及ぼす影響2016

    • Author(s)
      小野くみ子、道上可奈、杉本達也、杉山和也、高森公美、廣田勇士、坂口一彦、石川朗
    • Organizer
      第59回日本糖尿病学会年次学術集会
    • Place of Presentation
      みやこめっせ、京都
    • Year and Date
      2016-05-20
    • Related Report
      2016 Research-status Report
  • [Presentation] 水中トレッドミル歩行継続が高度肥満を伴う2型糖尿病患者の循環指標に及ぼす影響2014

    • Author(s)
      小野くみ子、杉本達也、杉山和也、高森公美、道上可奈、中島進介、廣田勇士、坂口一彦、石川朗
    • Organizer
      第51回日本糖尿病学会近畿地方会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-10-25
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2020-03-30  

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