Biological function of novel adrenomedullins in teleosts and amphibians: focusing on hematopoietic and immune system
| Project/Area Number |
26870386
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Evolutionary biology
Morphology/Structure
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| Research Institution | Okayama University |
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Principal Investigator |
Maho Ogoshi 岡山大学, 自然科学研究科, 助教 (00527997)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | アドレノメデュリン / 造血 / 脊椎動物 / メダカ / ネッタイツメガエル / 比較内分泌学 |
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| Outline of Final Research Achievements |
We examined the hematopoietic function of novel adrenomedullins in vertebrates. The AM3 gene expression was induced after hemolytic anemia in teleost fish, medaka, suggesting its role in erythropoiesis. In Xenopus tropicalis, AM5 mRNA was detected in the ventral blood island at tailbud stage embryo and was expressed in adult hematopoietic stem cells.
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Report
(3 results)
Research Products
(4 results)
