Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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Outline of Final Research Achievements |
Terapeutic resistance to radiation therapy and chemotherapy of glioma stem cells is a major hurdle in the treatment of malignant glioma. In this study, ALA-PDT was performed using glioma stem cell lines (3 cell lines of mesenchymal type and 2 cell lines of proneural type). As a result, it was found that ALA-PDT is more sensitive to glioma stem cells and has superior characteristics such as decreased stemness after PDT treatment.
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