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The developement for effectiveness of rehabilitation in obstructive sleep apnea

Research Project

Project/Area Number 26870760
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Clinical nursing
Rehabilitation science/Welfare engineering
Research InstitutionHimeji Dokkyo University

Principal Investigator

Kanezaki Masashi  姫路獨協大学, 医療保健学部, 講師 (10707871)

Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords閉塞型睡眠時無呼吸 / オトガイ舌筋 / 舌前方突出筋力 / 睡眠
Outline of Final Research Achievements

Although tongue protrusion strength by genioglossus activity during sleep contributes to the maintenance of airway patency in patients with OSA, the relationship between tongue protrusion strength in the arousal state and obstructive sleep apnea has not been fully elucidated. We investigated relationships between the tongue protrusion strength and polysomnographic findings. We enrolled twenty normal subjects and 26 subjects with OSA. All subjects completed the measurement of tongue protrusion strength. Each subject with OSA was evaluated by full polysomnography. The degree of tongue protrusion strength was assessed by maximum voluntary contraction against the tongue depressor connected with a strain gauge dynamometer. The tongue protrusion strength was negatively correlated with obstructive apnea time, apnea index (AI) and the percent of sleep stage 2. Tongue protrusion strength measured in the arousal state is predictive of the airway patency during sleep in OSA.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (10 results)

All 2015 2014

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results,  Acknowledgement Compliant: 2 results) Presentation (8 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Tongue Protrusion Strength in Arousal State Is Predictive of the Airway Patency in Obstructive Sleep Apnea2015

    • Author(s)
      Kanezaki M, Ogawa T, Izumi T.
    • Journal Title

      The Tohoku Journal of Experimental Medicine

      Volume: 236 Issue: 4 Pages: 241-245

    • DOI

      10.1620/tjem.236.241

    • NAID

      130005083527

    • ISSN
      0040-8727, 1349-3329
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Distractive Auditory Stimuli Alleviate the Perception of Dyspnea Induced by Low-Intensity Exercise in Elderly Subjects With COPD.2015

    • Author(s)
      Shingai K, Kanezaki M, Senjyu H.
    • Journal Title

      Respiratory Care

      Volume: in press

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] 舌前方突出筋力と閉塞型睡眠時無呼吸2015

    • Author(s)
      金崎雅史 、小川晃弘 、泉唯史
    • Organizer
      第25回日本呼吸ケア・リハビリテーション学会学術集会
    • Place of Presentation
      東京ベイ舞浜ホテルクラブリゾート
    • Year and Date
      2015-10-15
    • Related Report
      2015 Annual Research Report
  • [Presentation] Olfactory stimulation of TRPM8 agonist lessen the perception of dyspnea induced by constant load exercise in never-smoker2015

    • Author(s)
      Kanezaki M.
    • Organizer
      European Respiraotry Society International Congress 2015 in Amsterdam
    • Place of Presentation
      Amsterdam RAI
    • Year and Date
      2015-09-26
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effect of olfactory stimulation of TRPM8 agonist on perception of dyspnea induced by constant load exercise in healthy never-smokers. TRPM8 agonist on exercise-induced dyspnea.2015

    • Author(s)
      M. Kanezaki
    • Organizer
      第50回日本理学療法学術大会
    • Place of Presentation
      東京
    • Year and Date
      2015-06-05 – 2015-06-07
    • Related Report
      2014 Research-status Report
  • [Presentation] Effect of olfactory stimulation of TRPM8 agonist on perception of dyspnea induced by constant load exercise in healthy never-smokers.TRPM8 agonist on exercise-induced dyspnea2015

    • Author(s)
      Kanezaki M
    • Organizer
      第50回日本理学療法学術集会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2015-06-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] IP患者におけるBreath‐holding testを用いた新たな呼吸困難感評価法の開発2014

    • Author(s)
      新貝和也,金崎雅史,小川智也,渡邉文子,平澤純,田中裕子,三嶋卓也,古川拓朗,長江優介,谷口博之
    • Organizer
      第24回呼吸ケアリハビリテーション学会学術集会
    • Place of Presentation
      奈良
    • Year and Date
      2014-10-24 – 2014-10-25
    • Related Report
      2014 Research-status Report
  • [Presentation] The strength of genioglossus in the arousal state contributes the airway patency in patients with OSAS2014

    • Author(s)
      M. Kanezaki, A. Ogawa, A. Masaki
    • Organizer
      European Respiratory Society International Congress
    • Place of Presentation
      Munich, Germany
    • Year and Date
      2014-09-06 – 2014-09-10
    • Related Report
      2014 Research-status Report
  • [Presentation] 覚醒時オトガイ舌筋筋力と睡眠呼吸障害との関連についての検討2014

    • Author(s)
      金崎 雅史、小川 晃弘、泉 唯史
    • Organizer
      日本睡眠学会第39回定期学術集会
    • Place of Presentation
      徳島
    • Year and Date
      2014-07-04 – 2014-07-05
    • Related Report
      2014 Research-status Report
  • [Presentation] COPD患者におけるBreath-holding testによる新たな呼吸困難感評価法の開発2014

    • Author(s)
      新貝和也, 金崎雅史, 岡本一紀, 谷口博之, 小川智也, 渡邉文子, 平澤純, 三嶋卓也, 田中裕子, 古川拓朗, 長江優介, 津田徹
    • Organizer
      第49回日本理学療法学術大会
    • Place of Presentation
      横浜
    • Year and Date
      2014-05-30 – 2014-06-01
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2017-05-10  

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