| Project/Area Number |
26870775
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied pharmacology
General physiology
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| Research Institution | Tokushima Bunri University |
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Principal Investigator |
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| Research Collaborator |
Konishi shiro 徳島文理大学, 香川薬学部, 教授
Kobayashi Masayuki 日本大学, 歯学部, 教授
Kaneko Shuji 京都大学, 大学院薬学研究科, 教授
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 側坐核 / 拘束ストレス / セロトニン / ドパミン / 前頭前野 / 抑制性神経伝達 |
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| Outline of Final Research Achievements |
In this study, we clarified the dopaminergic modulation onto the GABAergic inhibitory synaptic transmission in nucleus accumbens of the normal rats or mice (Kohnomi et al., 2015, 2017).
we showed that daily restraint stress (for １ week) altered the function of serotonergic nervous system in medial prefrontal cortex and nucleus accumbens. This mild stress did not influence the dopaminergic functions.
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