Study for a similarity detection algorithm between very noisy diffraction patterns from XFEL
| Project/Area Number |
26870852
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Quantum beam science
Biophysics
|
|---|
| Research Institution | Institute of Physical and Chemical Research |
|---|
Principal Investigator |
Tokuhisa Atsushi 国立研究開発法人理化学研究所, 計算科学研究機構, 研究員 (60455300)
|
|---|
| Research Collaborator |
GO Nobuhiro 京都大学, 名誉教授
|
|---|
| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
|---|
| Keywords | 類似性判定法 / X線回折像 / 生体高分子 / 実験条件 / X線自由電子レーザー / 単粒子構造解析 / XFEL / CDI / 性能評価 / ROC解析 / 分類器 / 到達分解能 / 計算コスト削減 / 類似性判定 / コヒーレントイメージング / 回折像 |
|---|
| Outline of Final Research Achievements |
In order to realize single particle diffraction imaging with high resolution, it is needed to extract useful signal from noisy diffraction pattern. In this research, we developed and improved an automatic algorithm to detect similarity between pairs of coherent diffraction patterns from an orientation-unknown single particle. We developed a Pre-Analysis step with optimized parameters to realize low computational cost by performing an efficiency evaluation based on ROC curves. We also aimed to construct multi steps similarity detection algorithm by combing with Pre-Analysis step and Main-Analysis step to realize similarity detection algorithm with the high-performance and low computational cost. We elucidated the switching wave-number between Pre-Analysis step and Main-Analysis step.
|
Report
(4 results)
Research Products
(10 results)
