An implantable neural bidirectional device for behavior experiments of small animals
Project/Area Number |
26882027
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Research Category |
Grant-in-Aid for Research Activity Start-up
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Allocation Type | Single-year Grants |
Research Field |
Brain biometrics
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Research Institution | Nara Institute of Science and Technology |
Principal Investigator |
Haruta Makito 奈良先端科学技術大学院大学, 物質創成科学研究科, 博士研究員 (40733663)
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Project Period (FY) |
2014-08-29 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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Keywords | CMOSイメージセンサ / 脳機能イメージング / 脳血流計測 / オプトジェネティクス / 生体埋植デバイス / 多点光刺激 |
Outline of Final Research Achievements |
We have developed an implantable neural bidirectional device for understanding brain functions in behavior experiments of small animals. This device has two functions which are optically detecting and controlling brain activities. In this study, we achieved the following results; (1) The device weights about 0.2 g which is much lighter than the weight of an adult mouse. (2) The device detected brain activities in the smart somatosensory cortex when the frontal limb was stimulated. (3) The device controlled brain activities using multi optical stimulations in a brain of channelrhodopsin2-NestinCre transgenic mice.
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Report
(3 results)
Research Products
(9 results)
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[Presentation] An Implantable Hemodynamic Imaging Device for Observing the Process of Recovery from Cerebrovascular Disease2015
Author(s)
Makito Haruta, Yoshinori Sunaga, Takahiro Yamaguchi, Hironari Takehara, Yasumi Ohta, Mayumi Motoyama, Hiroaki Takehara, Toshihiko Noda, Kiyotaka Sasagawa, Takashi Tokuda, Jun Ohta
Organizer
37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Place of Presentation
Milano(Italy)
Year and Date
2015-08-28
Related Report
Int'l Joint Research
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[Presentation] 動物の脳機能制御を可能にする無線多点光刺激デバイス2015
Author(s)
Makito Haruta, , Naoya Kamiyama, Takahiro Yamaguchi, Mayumi Motoyama, Mamiko Kawahara, Yasumi Ohta, Hiroaki Takehara, Toshihiko Noda, Kiyotaka Sasagawa, Takashi Tokuda, Jun Ohta
Organizer
第38回日本神経科学大会
Place of Presentation
神戸国際展示場(兵庫県神戸市)
Year and Date
2015-07-29
Related Report
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[Presentation] 埋め込み可能な小型脳血流イメージングデバイスの開発2015
Author(s)
春田 牧人, 須永 圭紀, 山口 貴大, 竹原 浩成 太田 安美, 元山 真由美, 竹原 宏明, 野田 俊彦, 笹川 清隆, 徳田 崇 , 太田 淳
Organizer
E部門総合研究会
Place of Presentation
九州大学医学部百年講堂(福岡県福岡市)
Year and Date
2015-07-03
Related Report
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