Characteristics of skeletal muscle volume in sarcopenia and aerobic exercise intervention

• Project/Area Number: 26882056
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Applied health science
• Research Institution: Fukuoka University
• Principal Investigator: Masahiro Ikenaga 福岡大学, スポーツ科学部, 助教 (90735573)
• Project Period (FY): 2014-08-29 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000); Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: サルコペニア / 高齢者 / MRI / 有酸素運動 / 運動介入 / 骨格筋容積 / 運動

Outline of Final Research Achievements

The first aim of this study was to investigate the characteristics of skeletal muscle volume in sarcopenia (Study 1). The second aim was to investigate the effects of the aerobic exercise (Slow-jogging) on skeletal muscle volume in older adults (Study 2).
We examined the volume of eleven muscles of the thigh using magnetic resonance imaging (MRI) in the study 1. Fifteen older adults of low skeletal muscle and strength (Sarcopenia, S group) and sixteen healthy older adults (non-sarcopenia, NS group) participated in study 1. In study 2, a total of 81 older adults were randomly divided into the exercise intervention group (Ex) and control group (Con) for 3 months.
Volume of the vastus lateralis (VL), vastus intermedius (VI), vastus medialis (VM), semitendinosus (ST), and adductor longus together with adductor brevis (AL+AB) decreased in S group compared with NS group in study 1. Study 2 showed that skeletal muscle volume increased only in Ex group after intervention period.

Research Products

• [Presentation] 地域高齢者を対象とした体力科学的アプローチによる認知症とサルコペニア予防の縦断研究―福岡那珂川研究― 体力・身体活動と4年間の認知機能変化の関係 (2016)
  • Author(s): 池永昌弘, 森下香澄, 松尾莉子, 古瀬裕次郎, 森村和浩, 山田陽介, 武田典子, 合馬慎二, 坪井義夫, 山田達夫, 上原吉就, 清永明, 桧垣靖樹, 田中宏暁, Nakagawa Study Group
  • Organizer: 第18回七隈パーキンソン・アルツハイマー研究
  • Place of Presentation: 福岡, 日本
  • Year and Date: 2016-04-09
• [Presentation] Effects of intermittent slow-jogging training on fitness and skeletal muscle mass in older Japanese: a randomized controlled trial (2015)
  • Author(s): M. Ikenaga, H. Tanaka, Y. Yamada, Y. Kose, K. Morimura, Y. Higaki, A. Kiyonaga, Nakagawa Study Group
  • Organizer: International Conference on Frailty & Sarcopenia Research, 2015
  • Place of Presentation: ボストン, アメリカ
  • Year and Date: 2015-04-28
  • Int'l Joint Research
• [Presentation] Effects of intermittent slow-jogging training on fitness and skeletal muscle mass in older Japanese: a randomized controlled trial (2015)
  • Author(s): Masahiro Ikenaga, Hiroaki Tanaka, Yosuke Yamada, Yujiro Kose, Kazuhiro Morimura, Yasuki Higaki, Akira Kiyonaga, Nakagawa Study Group
  • Organizer: International conference on Frailty & Sarcopenia Research
  • Place of Presentation: Boston, MA, USA
  • Year and Date: 2015-04-23 – 2015-04-25
• [Presentation] 体力科学的アプローチによる認知症とサルコペニア予防の縦断研究―福岡那珂川研究―至適運動強度を用いた有酸素性トレーニングの可能性 (2015)
  • Author(s): 森村和浩, 池永昌弘, 古瀬裕次郎, 三好伸幸, 武田典子, 山田陽介, 桧垣靖樹, 田中宏暁, Nakagawa Study group
  • Organizer: 第17回七隈パーキンソン・アルツハイマー研究
  • Place of Presentation: 福岡, 日本
  • Year and Date: 2015-04-04
• [Remarks] 福岡大学基盤研究機関 身体活動研究所
  • URL: http://www.fuipa.spo.fukuoka-u.ac.jp/
• [Remarks] 福岡大学 基盤研究機関 身体活動研究所 ホームページ
  • URL: http://www.fuipa.spo.fukuoka-u.ac.jp/