Research for pharmacological activity of gold nanocluster for a new anticancer agent
| Project/Area Number |
26886012
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Nanobioscience
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| Research Institution | Tokyo Metropolitan University |
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Principal Investigator |
Fujita Takashi 首都大学東京, 都市環境科学研究科, 特任助教 (30737565)
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| Project Period (FY) |
2014-08-29 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 金クラスター / 細胞毒性 / ナノ毒性 / 薬理活性 / ナノメディシン |
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| Outline of Final Research Achievements |
Cytotoxicity of oxide-supported gold nanoparticulate catalysts toward cancer cell lines were investigated. Among the investigated catalysts (Au/SiO2, Au/TiO2, Au/Fe2O3, Au/ZnO, and Au/ZrO2), Au/ZnO showed high cytotoxicity for HeLa and Mia Paca-2. Although simple ZnO also exhibits relatively high cytotoxicity compared to other oxides, this cytotoxicity further increased by deposition of gold nano clusters.
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Report
(3 results)
Research Products
(4 results)
