Development of surface plasmon-enhanced fluorescence biosensor for early detection of biomarkers
| Project/Area Number |
26889025
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Measurement engineering
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
Toma Koji 東京医科歯科大学, 生体材料工学研究所, 助教 (40732269)
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| Project Period (FY) |
2014-08-29 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 表面プラズモン / バイオセンサ / 蛍光 |
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| Outline of Final Research Achievements |
The purpose of this research was to develop an optical biosensor that enables sensitive measurement of marker biomolecules which are used to estimate a potential risk of diseases. In fiscal year 2014, a proper structure or material of a sensor chip were investigated by simulation, and an experimental setup and its controlling system were developed. In fiscal year 2015 year, along with optimizing and tuning the development of the setup and the system, a model sample of microparticles which correlate to inflammatory diseases, autoimmune disorder, and malignancies was measured. It was observed that the sensor output increased with increased concentration of the sample.
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Report
(3 results)
Research Products
(5 results)
