• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Anatomical identification of the multi-synaptic functional connectivity between frontal and temporal cortex of monkeys, responsible for memory recall.

Research Project

Project/Area Number 26890007
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Neurophysiology / General neuroscience
Research InstitutionThe University of Tokyo

Principal Investigator

Setsuie Rieko  東京大学, 医学(系)研究科(研究院), 特任研究員 (30532535)

Project Period (FY) 2014-08-29 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywordsmacaque monkey / functional MRI / memory recall / tracer / BDA / トレーサー / 安静時機能的磁気共鳴画像法 / マカクサル / 下部側頭葉 / 前頭葉 / 脳・神経 / 多シナプス性機能結合 / 機能的磁気共鳴画像法
Outline of Final Research Achievements

Prefrontal cortex and inferior temporal cortex are two important areas, involved in memory recall formation. However, the functional connectivity and its multi synaptic projection relays between these two areas have not been well identified. In this study, we trained macaque monkeys to perform recency test, a test which monkeys are asked to study many serially shown pictures. Then, monkeys are asked to choose one recently seen picture from two shown pictures. We performed functional MRI analysis when monkeys are performing these tasks in MRI. We found that area 9 in prefrontal cortex and area TE in inferior temporal cortex has functional connectivity and reported this result in a scientific journal.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • Research Products

    (5 results)

All 2015 2014 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results,  Acknowledgement Compliant: 2 results) Presentation (2 results) (of which Int'l Joint Research: 1 results) Remarks (1 results)

  • [Journal Article] Dynamically allocated hub in task-evoked network predicts the vulnerable prefrontal locus for contextual memory retrieval in macaques.2015

    • Author(s)
      Osada T., Adachi, Y., Miyamoto, K., Jimura, K., Setsuie, R., and Miyashita, Y.
    • Journal Title

      PLOS Biology

      Volume: 13(6) Issue: 6 Pages: 1-31

    • DOI

      10.1371/journal.pbio.1002177

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Dynamically allocated hub in task-evoked network predicts the vulnerable prefrontal locus for contexual memory retrieval in macaques2015

    • Author(s)
      T. Osada, Y. Adachi, K. Miyamoto, K. Jimura, R. Setsuie, and Y. Miyashita
    • Journal Title

      PLOS Biology

      Volume: in press

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] Hub-centric prefrontal network predicts lesion-effective site for contextual memory in macaques2015

    • Author(s)
      T. Osada, Y. Adachi, K. Miyamoto, K. Jimura, R. Setsuie, T. Watanabe, Y. Miyashita
    • Organizer
      Society of Neuroscience ( Neuroscience 2015)
    • Place of Presentation
      Chicago(米国)
    • Year and Date
      2015-10-17
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Dissociable memory formation processes within the macaque medial temporal lobe2014

    • Author(s)
      K. Miyamoto, Y. Adachi, T. Osada, T. Watanabe, R. Setsuie, H.M. Kimura, T. Watanabe, Y.Miyashita
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      Washington DC(米国)
    • Year and Date
      2014-11-15 – 2014-11-19
    • Related Report
      2014 Annual Research Report
  • [Remarks] 脳損傷や脳外科手術における後遺症の予測へ

    • URL

      https://www.juntendo.ac.jp/graduate/pdf/news19.pdf

    • Related Report
      2015 Annual Research Report

URL: 

Published: 2014-09-09   Modified: 2017-05-10  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi